Research of the efficacy of particle therapy against head and neck cancer

• Project/Area Number: 23791898
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Kobe University
• Principal Investigator: MORIMOTO Koichi 神戸大学, 医学部付属病院, 特定助教 (90457044)
• Co-Investigator(Kenkyū-buntansha): NIBU Ken-ichi 神戸大学, 医学研究科, 教授 (20251283)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 頭頸部癌 / 粒子線治療 / 国際情報交流

Research Abstract

Proton and carbon ion radiotherapy resulted in satisfactory local control in patients with locally advanced unresectable primary head and neck cancers invading the skull base. ACC and ONB were favorable pathologic types. Although severe late toxicities were observed in considerable patients, most of the late toxicities were acceptable when the extension of the cancer was taken into account.

Research Products

• [Journal Article] Four cases of spinal accessory nerve passing through the fenestrated internal jugular vein (2012)
  • Author(s): Hashimoto Y, Otsuki N, Morimoto K, Saito M, Nibu KI
  • Journal Title: Surg Radiol Anat Volume: (in press) Issue: 4 Pages: 373-375
  • DOI: 10.1007/s00276-011-0875-x
  • Peer Reviewed
• [Presentation] 当科における照射後再発喉頭癌に対する喉頭垂直部分切除例の検討 (2013)
  • Author(s): 森本 浩一
  • Organizer: 第25回日本喉頭科学会
  • Place of Presentation: 神奈川
  • Year and Date: 2013-03-07
• [Presentation] 当科における早期声門癌に対するCO2 レーザー切除術の治療成績 (2012)
  • Author(s): 森本 浩一
  • Organizer: 第64回日本気管食道科学会
  • Place of Presentation: 東京
  • Year and Date: 2012-11-08
• [Presentation] 高齢者喉頭癌患者に対する喉頭垂直部分切除の検討 (2012)
  • Author(s): 森本 浩一、大月 直樹、米澤 宏一郎、齋藤 幹、丹生 健一
  • Organizer: 第22回日本頭頸部外科学会総会
  • Place of Presentation: 福島
• [Presentation] Particle therapy using proton beams or carbon beams for unresectable locally advanced head and neck cancers with skull base invasion (2011)
  • Author(s): Koichi Morimoto
  • Organizer: 11th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
  • Place of Presentation: 神戸
  • Year and Date: 2011-12-08
• [Presentation] 頭蓋底浸潤を認めた頭頸部 癌に対する粒子線治療成績 (2011)
  • Author(s): 森本 浩一
  • Organizer: 第35回日本頭頸部癌学会
  • Place of Presentation: 愛知
  • Year and Date: 2011-06-10
• [Presentation] 頭蓋底浸潤を認めた頭頸部癌に対する粒子線治療成績 (2011)
  • Author(s): 森本 浩一、出水 祐介、寺嶋 千貴、美馬 正幸、藤井 收、丹羽 康江、宮脇 大輔、佐々木 良平、村上 昌雄、丹生 健一
  • Organizer: 第35回日本頭頸部癌学会総会
  • Place of Presentation: 名古屋
• [Presentation] 気管原発腺様嚢胞癌に対する炭素線治療経験 (2011)
  • Author(s): 森本 浩一、出水 祐介、土井 清司、村上 昌雄、丹生 健一
  • Organizer: 第63回日本気管食道科学会総会
  • Place of Presentation: 名古屋