| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Spasmodic dysphonia (SD) is a disease that lead to a strained/strangled, hoarse, and effortful voice and is increasing in recent years. It is considered that it is caused by the abnormality of the brain function although the pathophysiology of SD is unknown enough. We carried out functional magnetic resonance imaging (fMRI) for patients with SD and assessed their brain function. It showed dysfunctions of the basal ganglia and the parietal association area, which integrated a sense, by comparing the various vocalization tasks, and brain activities before and after surgery (type 2 thyroplasty).It was suggested the possibility that these areas were associated with the onset of the SD deeply.
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