Association with epithelial-mesenchymal trasition andcancer stem cell in Head and Neck cancer

• Project/Area Number: 23791933
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Keio University
• Principal Investigator: HABU Noboru 慶應義塾大学, 医学部, 助教 (60365369)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 頭頸部癌 / 癌幹細胞 / 国際情報交流

Research Abstract

Oct3/4 and Nanog are putative cancer stem cell markers in Head and Neck Squamous Cell Carcinoma and the reliable predictors of delayed neck metastasis.

Research Products

• [Presentation] Expressions of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell markers (2012)
  • Author(s): Noboru Habu, Yorihisa Imanishi
  • Organizer: 8thinternational conference on Head and Neck Cancer
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2012-07-25
• [Presentation] Expression of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinoma (2012)
  • Author(s): 羽生昇
  • Organizer: 8th International Conference on Head and Neck Cancer
  • Place of Presentation: トロント（カナダ）
• [Presentation] Expressions of stem cell markers Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell markers (2011)
  • Author(s): 羽生昇、今西順久、徳丸裕、藤井正人
  • Organizer: 第70回日本癌学会
  • Place of Presentation: 名古屋
  • Year and Date: 2011-10-05
• [Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞の存在と癌幹細胞マーカーの発現に関する検討 (2011)
  • Author(s): 羽生昇、今西順久、徳丸裕、藤井正人、小川郁
  • Organizer: 第35回頭頸部癌学会
  • Place of Presentation: 名古屋
  • Year and Date: 2011-06-12
• [Presentation] 頭頸部扁平上皮癌におけるがん幹細胞様細胞の存在とmarkerの発現に関する検討 (2011)
  • Author(s): 羽生昇
  • Organizer: 頭頸部癌学会
  • Place of Presentation: ウインク愛知（愛知県）
• [Presentation] Expression of stem cell markers in Oct3/4 and Nanog and its clinical significance in oral tongue squamous cell carcinoma (2011)
  • Author(s): 羽生昇
  • Organizer: 日本癌学会
  • Place of Presentation: 名古屋国際会議場（愛知県）