Observation of limbal stem cell niche using in vivo confocal microscope
| Project/Area Number |
23791962
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Osaka University |
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Principal Investigator |
OIE Yoshinori 大阪大学, 医学(系)研究科(研究院), 助教 (20599881)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Keywords | 眼発生・再生医学 / 角膜上皮幹細胞 / 再生医学 / 幹細胞 / 移植・再生医療 |
|---|
| Research Abstract |
Longest diameter and dimension of limbal basal cells were evaluated using in vivo confocal miscroscope (Heidelberg Retina Tomograph 2 Rostock Corneal Module) for patients with Harada disease. Sixteen eyes of nine patients were included. Average age was 51, 13 eyes with men, 3 eyes with women. Longest diameter and dimension of limbal basal cells in patients with Harada disease were 16.1um and 135um2, respectively. It was suggested that limbal basal cells in Harada disease were larger than in normal eyes because of destruction of melanocyte in limbal niche.
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Report
(4 results)
Research Products
(41 results)
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[Journal Article] Development of a cell sheet transportation technique for regenerative medicine2014
Author(s)
Oie Y, Nozaki T, Takayanagi H, Hara S, Hayashi R, Takeda S, Mori K, Moriya N, Soma T, Tsujikawa M, Saito K, Nishida K
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Journal Title
Tissue Eng Part C Methods
Volume: 20
Pages: 373-82
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[Presentation]2013
Author(s)
Yoshinori Oie, Takeshi Soma, Ryuhei Hayashi, Motokazu Tsujikawa, Kohji Nishida
Organizer
Termis-AP Meeting 2013
Place of Presentation
Wuzhen, 中国(口演)
Year and Date
2013-10-25
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