Regeneration of retinal function using human amnion cell-derived neural progenitors.
Project/Area Number |
23792013
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Ophthalmology
|
Research Institution | Nippon Medical School |
Principal Investigator |
KITAHARA Yuki 日本医科大学, 医学部, 助教 (30360176)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 再生医学 / 網膜再生 / 神経幹細胞 / 羊膜由来幹細胞 / 羊膜多能幹細胞 / 羊膜由来多能性幹細胞 |
Research Abstract |
Human amniotic membrane is already broadly transplanted to the ocular surface , the supply is abundant and is easy to obtain. Human amnion cell-derived neural progenitors can be isolated and cultured from human amnion obtained during cesarean section under the informed consent. Human amnion cell-derived neural progenitors obtain long-term survival in the subretinal space and possess the potential of differentiating to retinal cells. Regeneration of retinal function was suggestive using electroretinogram.
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Report
(3 results)
Research Products
(1 results)