Regeneration of retinal function using human amnion cell-derived neural progenitors.

Research Project

Project/Area Number	23792013
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Ophthalmology
Research Institution	Nippon Medical School
Principal Investigator	KITAHARA Yuki 日本医科大学, 医学部, 助教 (30360176)
Project Period (FY)	2011 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000) Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords	再生医学 / 網膜再生 / 神経幹細胞 / 羊膜由来幹細胞 / 羊膜多能幹細胞 / 羊膜由来多能性幹細胞
Research Abstract	Human amniotic membrane is already broadly transplanted to the ocular surface , the supply is abundant and is easy to obtain. Human amnion cell-derived neural progenitors can be isolated and cultured from human amnion obtained during cesarean section under the informed consent. Human amnion cell-derived neural progenitors obtain long-term survival in the subretinal space and possess the potential of differentiating to retinal cells. Regeneration of retinal function was suggestive using electroretinogram.

Report

(3 results)