Development of novel composite tissue allograft models using supermicrosurgery
| Project/Area Number |
23792039
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
IIDA Takuya 東京大学, 医学部附属病院, 特任講師 (00398603)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 組織移植 / 同種複合組織移植 / 超微小血管吻合 / 同種移植 |
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| Research Abstract |
Novel composite tissue allograft animal models were developed using the supermicrosurgical techniques. We focused on mainly two models as follows; eye transplantation model using rabbits and uterus transplantation model using cynomolgus monkeys. Several problems in application of these models to clinical cases were noted such as optic nerve regeneration in eye model and pregnancy in uterus model, and thus several experiments were performed to solve these problems.
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Report
(3 results)
Research Products
(12 results)
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[Journal Article] Pathological steps of cancer-related lymphedema: histological changes in the collecting lymphatic vessels after lymphadenectomy2012
Author(s)
Mihara M, Hara H, Hayashi Y, Narushima M, Yamamoto T, Todokoro T, Iida T, Sawamoto N, Araki J, Kikuchi K, Murai N, Okitsu T, Kisu I, Koshima I
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Journal Title
Related Report
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[Journal Article] Uterine autotransplantation in cynomolgus macaques: the first case of pregnancy and delivery2012
Author(s)
Mihara M, Kisu I, Hara H, Iida T, Araki J, Shim T, Narushima M, Yamamoto T, Moriguchi H, Kato Y, Tonsho M, Banno K,Aoki D, Suganuma N, Kagawa N, Takehara Y, Kato O, Koshima I
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Journal Title
Hum Reprod
Volume: 27(8)
Pages: 2332-40
Related Report
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[Journal Article] Indocyanine green fluorescence imaging for evaluation of uterine blood flow in cynomolgus macaque2012
Author(s)
Kisu I, Banno K, Mihara M, Lin LY, Tsuji K, Yanokura M, Hara H, Araki J, Iida T, Abe T, Kouyama K, Suganuma N, Aoki D
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Journal Title
Related Report
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[Journal Article] Uterus autotransplantation in cynomolgus macaques: intraoperative evaluation of uterine blood flow using indocyanine green2011
Author(s)
Mihara M, Kisu I, Hara H, Iida T, Yamamoto T, Araki J, Hayashi Y, Moriguchi H, NarushimaM, Banno K, Suganuma N, Aoki D, Koshima I
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Journal Title
Hum Reprod
Volume: 26(11)
Pages: 3019-27
Related Report
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