Genome sequencing and mutational analysis of the Actinomyces strains with enhanced biofilm phenotype
Project/Area Number |
23792118
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Morphological basic dentistry
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Research Institution | Osaka Dental University |
Principal Investigator |
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Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | 口腔細菌学 / バイオフィルム / 口腔細菌 |
Research Abstract |
To find out the mechanism of biofilm formation of oral Actinomyces, genome and genetic analysis were carried out for two strains of K20 and MG-1 keeping enhanced biofilm phenotype. The genome of the strain K20 was almost completely sequenced and the given data was uploaded to the public database(DDBJ, BABV01000001-BABV01000771). Additionally, I have identified some biofilm-related genes by mutation analysis and have reported this.
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Report
(3 results)
Research Products
(33 results)
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[Journal Article] Biofilm-forming capacity on clinically isolated Streptococcus constellatus from an odontogenic subperiosteal abscess lesion2013
Author(s)
Yamanaka T, Furukawa T, Yamane K, Nambu T, Mashimo C, Maruyama H, Inoue J, Kamei M, Yasuoka H, Horiike S, Leung KP, Fukushima H
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Journal Title
Journal of Bacteriology & Parasitology
Volume: 4
Issue: 01
Pages: 1000160-1000160
DOI
Related Report
Peer Reviewed
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[Journal Article] Identification of the genes involved in the biofilm-like structures on Actinomyces oris K20, a clinical isolate from an apical lesion2013
Author(s)
Mashimo C, Kamitani M, Nambu T, Yamane K, Yamanaka T, Tatami T, Inoue J, Kamei M, Morita S, Fukushima H
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Journal Title
Jounal of Endodontics
Volume: 39(1)
Issue: 1
Pages: 44-48
DOI
Related Report
Peer Reviewed
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