Properties of the neural circuit involved in coordination ofmastication movements

• Project/Area Number: 23792131
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Functional basic dentistry
• Research Institution: Showa University
• Principal Investigator: NISHIMURA Akiko 昭和大学, 歯学部, 助教 (00551227)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 口腔生理学 / 咀嚼運動 / 協調運動制御 / 三叉神経運動核 / 顔面神経運動核 / プレモータニューロン / 顔面神経核

Research Abstract

Properties of the neural circuit involved in coordination of mastication movements is not clear. The aim of present study was to investigate synaptic transmission from the reticular formation dorsal to the facial nucleus to trigeminal and facial motoneurons using voltage-sensitive dye, laser photostimulation and patch-clamp recordings. Our results suggest that inputs from the reticular formation dorsal to the facial nucleus to trigeminal and facial motoneurons influence the coordination of mastication movements.

Research Products

• [Journal Article] FRET-based evaluation of Bid cleavage in a single primary cultured neuron (2012)
  • Author(s): Nakazawa H, Nsihimura A, Suga K, MishimaT, Yorozu T, Iijima T
  • Journal Title: Neurosci Lett
  • Peer Reviewed
• [Journal Article] Convergent Pre-motoneuronal Inputs to Single Trigeminal Motoneurons (2012)
  • Author(s): Nonaka M, Nishimura A, Nakamura S, Nakayama K, Mochizuki A, Iijima T Inoue T
  • Journal Title: J Dent Res Volume: 91(9)
  • Peer Reviewed
• [Presentation] 下顎・頬・口唇の協調運動に関与する神経回路の解析 (2011)
  • Author(s): 西村晶子、中村史朗、野中睦美、飯島毅彦、井上富雄
  • Organizer: Journal of Oral Biosciences
• [Presentation] 三叉神経運動ニューロンには三叉神経運動核周囲の様々な部位からの入力が収束する (2011)
  • Author(s): 野中睦美、西村晶子、中山希世美、中村史朗、望月文子、飯島毅彦、井上富雄
  • Organizer: 第47回日本顎口腔機能学会学術集会プログラム抄録集
• [Presentation] Electrophysiological and morphological properties of premotor neurons targeting jaw-closing and jaw-opening motoneurons (2011)
  • Author(s): Inoue T, Nakamura S, Gemba-Nishimura A, Nonaka M, Yoshida A, Mochizuki A and Nakayama K
  • Organizer: Society for Neuroscience's 40^<th> annual meeting
• [Presentation] 下顎・頬・口唇の協調運動制御に関与する神経回路の解析 (2011)
  • Author(s): 西村晶子 中村史朗 野中睦美 飯島毅彦 井上富雄
  • Organizer: 第53回歯科基礎医学会学術大会・総会
  • Place of Presentation: 長良川国際会議場
• [Presentation] 三叉神経運動ニューロンには三叉神経運動核周囲の様々な部位からの入力が収束する (2011)
  • Author(s): 野中睦美 西村晶子 中山希世美 中村史朗 望月文子 飯島毅彦 井上富雄
  • Organizer: 第47回日本顎口腔機能学会学術集会
  • Place of Presentation: 兵庫医療大学 神戸キャンパス
• [Presentation] Inoue T, Nakamura S, Gemba-Nishimura A, Nonaka M, Yoshida A, Mochizuki A, Nakayama K (2011)
  • Author(s): Electrophysiological and morphological properties of premotor neurons targeting jaw-closing and jaw-opening motoneurons
  • Organizer: Society for Neuroscience's 40th annual meeting(招待講演)
  • Place of Presentation: Washington DC