| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
Dental pulp is important for maintenance of tooth function.Therefore, it is beneficial to establish the dentin-pulp complex regeneration therapy. Wehave tried to develop the strategy that regeneration of the dentin-pulp complex fromamputated dental pulp. In this study, we found that mild heat stress inducedthermo-resistance on odontoblastic lineage cells and heat stress or BMP-2 enhanced thatthe cells differentiated into odontoblast. These finding contributes to the establishment ofdentin-pulp complex regeneration therapy from amputated dental pulp.
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