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Videoendoscopic and optimum pressure on continuous positive airway pressure diagnosis for predicting the response to the oral appliance therapy in obstructive sleep apnea syndrome

Research Project

Project/Area Number 23792217
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthetic dentistry
Research InstitutionOsaka University

Principal Investigator

OKUNO Kentaro  大阪大学, 歯学部附属病院, 医員 (50420451)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords歯学 / 福祉 / ストレス / 診断 / 睡眠障害 / 閉塞性睡眠時無呼吸症候群 / 睡眠呼吸障害 / 口腔内装置 / 経鼻的持続陽圧呼吸療法
Research Abstract

Predicting which patients will respond to oral appliance (OA) therapy in obstructive sleep apnea (OSA) is not yet possible, although there are several studies of practice parameters predicting treatment outcome. We report herein additional data and findings for the purpose of predicting OA treatment outcome using nasopharyngeal fiberscope (NPF) and optimum pressure on continuous positive airway pressure (CPAP). The effects of OA therapy can be expected in the presence of velopharyngeal side, oropharyngeal side and front widening on NPF findings by advancing the mandible and in the presence of low pressure on CPAP. Thus, to determine whether OA therapy is indicated, endoscopic evaluation of morphological changes with mandibular advancement and optimum pressure on CPAP may be important.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (37 results)

All 2014 2013 2012 2011

All Journal Article (13 results) (of which Peer Reviewed: 8 results) Presentation (24 results) (of which Invited: 6 results)

  • [Journal Article] The effect of oral appliances that advanced the mandible forward and limited mouth opening in patients with obstructive sleep apnea: A systematic review and meta-analysis of randomised controlled trials2014

    • Author(s)
      Okuno K, Sato K, Arisaka T, Hosohama K, Gotoh M, Taga H, Sasao Y, Hamada S
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: Now printing Issue: 7 Pages: 542-554

    • DOI

      10.1111/joor.12162

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Videoendoscopic diagnosis for predicting the response to oral appliance therapy in severe obstructive sleep apnea2014

    • Author(s)
      Sasao Y, Nohara K, Okuno K, Nakamura Y,Sakai T
    • Journal Title

      Sleep Breath

    • NAID

      130005405106

    • Related Report
      2013 Final Research Report
  • [Journal Article] Videoendoscopic diagnosis for predicting the response to oral appliance therapy in severe obstructive sleep apnea2014

    • Author(s)
      Sasao Y, Nohara K, Okuno K, Nakamura Y, Sakai T
    • Journal Title

      Sleep and Breathing

      Volume: Now printing

    • NAID

      130005405106

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 閉塞性睡眠時無呼吸症候群に対するオーダーメイド医療2013

    • Author(s)
      奥野健太郎,野原幹司,阪井丘芳
    • Journal Title

      日本統合医療学会

      Volume: 6(1) Pages: 40-43

    • NAID

      40019750281

    • Related Report
      2013 Final Research Report
  • [Journal Article] 閉塞性睡眠時無呼吸症候群に対するオーダメイド医療2013

    • Author(s)
      奥野健太郎、野原幹司、阪井丘芳
    • Journal Title

      日本統合医療学会誌

      Volume: 6 Pages: 40-43

    • NAID

      40019750281

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a swallowing frequency meter using a laryngeal microphone2012

    • Author(s)
      Tanaka N, Nohara K, Okuno K, Kotani Y, Okazaki H, Matsumura M, Sakai T
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: (印刷中) Issue: 6 Pages: 411-420

    • DOI

      10.1111/j.1365-2842.2012.02293.x

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 閉塞性睡眠時無呼吸症候群への対応-歯科だからできる検査・診断・治療-2012

    • Author(s)
      奥野健太郎,野原幹司,阪井丘芳
    • Journal Title

      歯科展望

      Volume: 120(6) Pages: 996-1005

    • Related Report
      2013 Final Research Report
  • [Journal Article] 口腔内装置治療により睡眠時無呼吸症候群に伴う心室性期外収縮が改善した1症例2012

    • Author(s)
      奥野健太郎,佐々生康宏,中村 祐己,野原幹司,阪井丘芳
    • Journal Title

      日本口腔科学会雑誌

      Volume: 61(4) Pages: 331-336

    • NAID

      10031144865

    • Related Report
      2013 Final Research Report
  • [Journal Article] 【閉塞性睡眠時無呼吸症候群への対応-歯科だからできる検査・診断・治療-】 睡眠時無呼吸症候群の基礎知識2012

    • Author(s)
      奥野 健太郎, 野原 幹司, 阪井 丘芳
    • Journal Title

      歯界展望

      Volume: 120巻6号 Pages: 996-1005

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 口腔内装置治療により睡眠時無呼吸症候群に伴う心室性期外収縮が改善した1症例2012

    • Author(s)
      奥野 健太郎, 佐々生 康宏, 中村 祐己, 野原 幹司, 阪井 丘芳
    • Journal Title

      日本口腔科学会雑誌

      Volume: 61巻4号 Pages: 331-336

    • NAID

      10031144865

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of a swallowing frequency meter using a laryngeal microphone2012

    • Author(s)
      Tanaka N, Nohara K, Okuno K
    • Journal Title

      J Oral Rehabil

      Volume: 39 Pages: 411-420

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 睡眠呼吸障害における歯科の役割~歯科との連携,総合臨床2011

    • Author(s)
      佐々生康宏,奥野健太郎,他
    • Journal Title

      永井出版

      Volume: 60(8) Pages: 1700-1708

    • Related Report
      2013 Final Research Report
  • [Journal Article] 睡眠呼吸障害における歯科の役割 -歯科との連携-2011

    • Author(s)
      佐々生康宏、奥野健太郎、他
    • Journal Title

      綜合臨牀

      Volume: 60 Pages: 1700-1708

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 各睡眠段階における嚥下反射の変化2013

    • Author(s)
      奥野健太郎、野原幹司、中村祐己、阪井丘芳
    • Organizer
      第38回日本睡眠学会
    • Place of Presentation
      秋田
    • Year and Date
      2013-06-28
    • Related Report
      2013 Final Research Report
  • [Presentation] 睡眠中の嚥下動態2013

    • Author(s)
      奥野健太郎
    • Organizer
      第38回日本睡眠学会
    • Place of Presentation
      秋田
    • Year and Date
      2013-06-28
    • Related Report
      2013 Final Research Report
  • [Presentation] The effect of oral appliances in patients with obstructive sleep apnea - A systematic review and meta-analysis of randomized controlled trials-2013

    • Author(s)
      Okuno K, Sato K, Arisaka T, Hosohama K, Gotoh M, Taga H, Sasao Y, Hamada S
    • Organizer
      AADSM 22nd annual meeting
    • Place of Presentation
      Baltimore USA
    • Related Report
      2013 Final Research Report
  • [Presentation] 夜間の口腔乾燥症と睡眠時無呼吸症候群との関連性の検討~鼻咽腔内視鏡を用いた機能的解析~2013

    • Author(s)
      阪井丘芳、奥野健太郎、野原幹司、佐々生康宏、小谷泰子
    • Organizer
      第6回日本口腔検査学会総会・学術大会
    • Place of Presentation
      鶴見大学
    • Related Report
      2013 Final Research Report
  • [Presentation] The effect of oral appliances in patients with obstructive sleep apnea - A systematic review and meta-analysis of randomized controlled trials-2013

    • Author(s)
      Okuno K, Sato K, Arisaka T, Hosohama K, Gotoh M, Taga H, Sasao Y, Hamada S
    • Organizer
      The American Academy of Dental Sleep Medicine Annual meeting
    • Place of Presentation
      Baltimore
    • Related Report
      2013 Annual Research Report
  • [Presentation] 睡眠中の嚥下動態2013

    • Author(s)
      奥野健太郎、野原幹司、中村裕己、阪井丘芳
    • Organizer
      日本睡眠学会定期学術集会
    • Place of Presentation
      秋田
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 各睡眠段階における嚥下反射の変化2013

    • Author(s)
      奥野健太郎、野原幹司、中村祐己、阪井丘芳
    • Organizer
      日本睡眠学会定期学術集会
    • Place of Presentation
      秋田
    • Related Report
      2013 Annual Research Report
  • [Presentation] 口腔内スプリントにより日中の眠気と健忘症状が改善した閉塞性睡眠時無呼吸症候群の1例2013

    • Author(s)
      木村紀久、奥野健太郎、佐古田三郎
    • Organizer
      日本臨床睡眠医学会 学術集会
    • Place of Presentation
      兵庫
    • Related Report
      2013 Annual Research Report
  • [Presentation] 夜間の口腔乾燥症と睡眠時無呼吸症候群との関連性の検討~鼻咽腔内視鏡を用いた機能的解析~2013

    • Author(s)
      阪井丘芳、奥野健太郎、野原幹司、佐々生康宏、小谷泰子
    • Organizer
      日本口腔検査学会総会・学術大会
    • Place of Presentation
      神奈川
    • Related Report
      2013 Annual Research Report
  • [Presentation] 口腔内スプリントにより日中の眠気と健忘症状が改善した閉塞性睡眠時無呼吸症候群の1例2012

    • Author(s)
      木村紀久、奥野健太郎、佐古田三郎
    • Organizer
      第5回ISMSJ学術集会
    • Place of Presentation
      兵庫
    • Year and Date
      2012-12-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 閉塞性睡眠時無呼吸症候群に対するオーダメイド医療について考える2012

    • Author(s)
      奥野健太郎、野原幹司、阪井丘芳
    • Organizer
      日本統合医療学会
    • Place of Presentation
      大阪
    • Year and Date
      2012-12-08
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 睡眠時無呼吸症の成人例から小児期での予防的アプローチを考える2012

    • Author(s)
      奥野健太郎,阪井丘芳
    • Organizer
      東北矯正歯科学会
    • Place of Presentation
      仙台
    • Year and Date
      2012-11-23
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] 閉塞性睡眠時無呼吸症候群に対する口腔内装置の診療ガイドライン作成の中間報告2012

    • Author(s)
      奥野健太郎
    • Organizer
      第11回日本睡眠歯科学会
    • Place of Presentation
      東京
    • Year and Date
      2012-11-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 閉塞型睡眠時無呼吸症候群における内視鏡検査を用いた口腔内装置治療の適応症の診断2012

    • Author(s)
      奥野健太郎,佐々生康宏,中村祐己,野原幹司,阪井丘芳
    • Organizer
      第37回日本睡眠学会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-28
    • Related Report
      2013 Final Research Report
  • [Presentation] Comparison of swallowing reflex during sleep and while awake2012

    • Author(s)
      Okuno K, Nohara K, Wakasugi Y, Sakai T
    • Organizer
      DRS 20th annual meeting
    • Related Report
      2013 Final Research Report
  • [Presentation] 口腔領域OSAS研究アップデート 閉塞型睡眠時無呼吸症候群における内視鏡検査を用いた口腔内装置治療の適応症の診断2012

    • Author(s)
      奥野 健太郎, 佐々生 康宏, 中村 祐己, 野原 幹司, 阪井 丘芳
    • Organizer
      日本睡眠学会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Comparison of swallowing reflex during sleep and while awake2012

    • Author(s)
      奥野 健太郎
    • Organizer
      The Dysphagia Research Society
    • Place of Presentation
      カナダ トロント
    • Related Report
      2011 Research-status Report
  • [Presentation] 口腔内装具治療を行った閉塞性睡眠時無呼吸症候群の1症例における診断と効果確認時PSG所見に関する検討2011

    • Author(s)
      野々上茂、奥野健太郎、三上章良
    • Organizer
      第3回Integrated Sleep Medicine Society Japanシンポジウム
    • Place of Presentation
      兵庫
    • Year and Date
      2011-08-26
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 口腔内装置の適応症の診断~内視鏡検査を用いて~2011

    • Author(s)
      奥野健太郎
    • Organizer
      第10回日本睡眠歯科学会シンポジウム
    • Place of Presentation
      愛知
    • Year and Date
      2011-07-03
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 口腔内装置装着によりCPAP至適圧が減少した1症例2011

    • Author(s)
      奥野健太郎, 他4名
    • Organizer
      日本睡眠学会誌
    • Place of Presentation
      (36:198)
    • Related Report
      2013 Final Research Report
  • [Presentation] 口腔内装置の適応症の診断~内視鏡検査を用いて~2011

    • Author(s)
      奥野健太郎
    • Organizer
      日本睡眠歯科学会
    • Place of Presentation
      愛知
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 口腔内装具治療を行った閉塞性睡眠時無呼吸症候群の1症例における診断と効果確認時PSG所見に関する検討2011

    • Author(s)
      野々上茂、奥野健太郎、三上章良
    • Organizer
      Integrated Sleep Medicine Society Japan
    • Place of Presentation
      兵庫
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 口腔内装置の適応症の診断~内視鏡検査を用いて~2011

    • Author(s)
      奥野 健太郎
    • Organizer
      日本睡眠歯科学会(招待講演)
    • Place of Presentation
      名古屋
    • Related Report
      2011 Research-status Report
  • [Presentation] 口腔内装置装着によりCPAP至適圧が減少した1症例2011

    • Author(s)
      奥野 健太郎
    • Organizer
      日本睡眠学会
    • Place of Presentation
      京都
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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