The influence between the recovery of the occlusal support after tooth extraction and the chronic stress

• Project/Area Number: 23792226
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthetic dentistry
• Research Institution: Okayama University
• Principal Investigator: KUROZUMI Akimasa 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20599790)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 咬合支持 / 臼歯抜歯 / 慢性ストレス

Research Abstract

Occlusal disturbance caused by the extraction of molar teeth or occlusal disharmony accelerate impairment of spatial learning and memory. It is possible that the loss of occlusal support by teeth extraction caused adecline of the spatial memory, and the recovery of occlusal support wearing the experimental denture controlled a decline of the spatial memory. Also, it was suggested that the loss of occlusal support caused a decline of hippocampus pyramidal cell density. Compared to chronic stress, it was not significant difference between control, denture-wearing, and tooth extraction groups. While wearing the experimental denture wasn’t under stress, the chronic stress caused by occlusal disharmony was not accepted.

Research Products

• [Presentation] Contralateral Hippocampal Pyramidal Cells is Reduced by Unilateral Tooth Extraction (2013)
  • Author(s): T. HARA, T. MIYAZAKI, S. SAKAMOTO, S. IIDA, D. ARAKI, A. KUROZUMI, C. KURODA-ISHIMINE, M. OKA, and S. MINAGI
  • Organizer: The IADR/AADR/CADR General Session and Exhibition
  • Place of Presentation: Seattle, U.S.A
  • Year and Date: 2013-03-23
• [Presentation] Effect of cyclic compressive force in rat gingival fibroblasts (2012)
  • Author(s): D. ARAKI, K. KAWATA, T. HARA, S. IIDA, M. OKA, C. KURODA-ISHIMINE, A. KUROZUMI, S. SAKAMOTO, T. MIYAZAKI, and S. MINAGI
  • Organizer: The 60th Annual Meeting of IADR Japanese Division
  • Place of Presentation: Niigata
  • Year and Date: 2012-12-15
• [Presentation] Adaptation of PMMA/divinyl adipate resin for denture base (2012)
  • Author(s): T. HARA, J. TANAKA, S. IIDA, D. ARAKI, T. MIYAZAKI, S. SAKAMOTO, C. KURODA, A. KUROZUMI, M. OKA, T. MATSUMOTO, and S. MINAGI
  • Organizer: The AADR Annual Meeting to be held in Tampa
  • Place of Presentation: Fla. USA
  • Year and Date: 2012-03-24
• [Presentation] Memory-related gene expression in the rat hippocampus by the learning (2012)
  • Author(s): S. IIDA, D. ARAKI, T. HARA, C. KURODA, M. OKA, A. KUROZUMI, K. KAWATA, S. SAKAMOTO, T. MIYAZAKI and S.MINAGI
  • Organizer: The AADR Annual Meeting to be held in Tampa
  • Place of Presentation: Fla. USA
  • Year and Date: 2012-03-24
• [Presentation] Effect of cyclic compressive force in rat gingival fibroblasts. (2012)
  • Author(s): D. ARAKI, K. KAWATA, T. HARA, S. IIDA, M. OKA, C. KURODA-ISHIMINE, A. KUROZUMI, S. SAKAMOTO, T. MIYAZAKI, and S. MINAGI,
  • Organizer: The 60th Annual Meeting of IADR Japanese Division
  • Place of Presentation: 新潟
• [Presentation] Memory-related gene expression in the rat hippocampus by the learning (2012)
  • Author(s): S. IIDA, D. ARAKI, T. HARA, C. KURODA, M. OKA, A. KUROZUMI, K. KAWATA, S. SAKAMOTO, T. MIYAZAKI, and S. MINAGI
  • Organizer: AADR Annual Meeting
  • Place of Presentation: Tampa, Fla. USA.
• [Presentation] 咬合支持回復時の空間認知脳に対する分散学習の影響 (2011)
  • Author(s): 原 哲也,黒住明正,坂本隼一,飯田祥与,荒木大介,黒田知沙,岡森彦,白井肇,皆木省吾,森慎吾,衣田圭宏
  • Organizer: 第22回老年歯科医学会
  • Place of Presentation: 東京
  • Year and Date: 2011-06-25
• [Presentation] 長期間咬合支持を喪失させたラットにおける咬合支持の回復が空間認知脳に与える影響 (2011)
  • Author(s): 坂本隼一,原 哲也,黒住明正,岡 森彦,黒田知沙,河田かずみ,荒木大介,飯田祥与,皆木省吾
  • Organizer: 第120回日本補綴歯科学会
  • Place of Presentation: 広島
  • Year and Date: 2011-05-20
• [Presentation] 長期間咬合支持を喪失させたラットにおける咬合支持の回復が空間認知能に及ぼす影響
  • Author(s): 坂本隼一，原 哲也，黒住明正，岡 森彦，黒田知沙，河田かずみ，荒木大介，飯田祥与，皆木省吾
  • Organizer: 第120回日本補綴歯科学会
  • Place of Presentation: 広島