Project/Area Number |
23792235
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Prosthetic dentistry
|
Research Institution | Kyushu University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 再生医療 / 補綴装置 / セメント質 / 再生歯学 / 歯原性上皮細胞 / マラッセの上皮遺残細胞 |
Research Abstract |
At present prosthesis treatments such as crown/bridge, removable denture and dentalimplant are commonly performed. On the other hand, trauma or congenital/aquiried tooth defect is stored by artificial materials have various issues in terms of biocompability, esthetics, functoionality, compared to natural teeth. This study delineates how regenerative therapy is applied to clinical dentistry. As a first step, we examined tooth regeneration which applied tissue engineering technique, especially cementum regeneration and tooth prosthesis materials. Recently, it is found that not only does cementum regenetration take a long period to complete tissue regeneration but also turn regenerated tissue premature and small. This research examines how cultured odontogenic cell stratification will affect the ability of cell growth and differentiation and tissue regeneration. Then, it intends to prove cell culture and tissue regeneration method quantitavely and qualitively.
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