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Study on the cerebral and systemic changes caused by chewing of the foods with different taste and odor

Research Project

Project/Area Number 23792263
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthetic dentistry
Research InstitutionHyogo Medical University

Principal Investigator

HASEGAWA Yoko  兵庫医科大学, 医学部, 助教 (60432457)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords咀嚼 / 味と香り / 脳血流 / ストレス / 情動 / 脳循環 / 体循環 / 自律神経活動
Research Abstract

In this study, we examined the changes in cerebral blood flow, systemic circulation, and autonomic nerve activity (heart rate and blood pressure variability analysis) during chewing of gum with various tastes and odors in order to investigate the effect of changes in taste and odor on these values. The result was that chewing of gum with taste and odor increased the cerebral blood flow most, suggesting that intake of foods with taste is important for activation of circulation system such as cerebral circulation. Furthermore, we measured the amount of secreted cortisol in saliva during chewing of gum in order to investigate the stress response to the chewing of gum with different tastes and odors. The results was that the gum with sweetness and lemon odor tasted best, and when chewing this gum, the amount of saliva secreted during chewing and the concentration of cortisol in saliva were higher than when chewing the other five gums. These results indicated that chewing of gum withtaste and odor, which was delicious for the subjects, causes more secretion of cortisol, an anti-stress hormone.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (17 results)

All 2013 2012 2011

All Journal Article (8 results) (of which Peer Reviewed: 3 results) Presentation (9 results)

  • [Journal Article] Flavor-enhanced modulation of cerebral blood flow during gum chewing.2013

    • Author(s)
      Hasegawa Y, Tachibana Y, Sakagami J, Zhang M, Urade M, Ono T.
    • Journal Title

      PLOS ONE.

    • URL

      http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066313

    • Related Report
      2012 Final Research Report
  • [Journal Article] Contrast enhanced multidetector CT for odontogenic cysts and cystic appearing tumors of the jaws: Is it useful2013

    • Author(s)
      Kakimoto N, Chindasombatjaroen J, Tomita S, Shimamoto H, UchiyamaY, Hasegawa Y, et al.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol;

      Volume: 115 Pages: 104-113

    • URL

      http://dx.doi.org/10.1016/j.oooo.2012.09.082

    • Related Report
      2012 Final Research Report
  • [Journal Article] Comparison of Joint Pain between Related and Unrelated to Articular Disc Displacement without Reduction in the Temporomandibular Joint.2013

    • Author(s)
      Fujiwara M, Honda K, Hasegawa Y, Hasegawa M, Urade M.
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod;

    • URL

      http://dx.doi.org/10.1016/j.oooo.2012.11.012

    • Related Report
      2012 Final Research Report
  • [Journal Article] Flavor-enhanced modulation of cerebral blood flow during gum chewing2013

    • Author(s)
      Hasegawa Yoko
    • Journal Title

      PLOS ONE

      Volume: in press

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Movement of the mandibular condyle and articular disc on placement of an occlusal splint Reply.2012

    • Author(s)
      Hasegawa Y
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod.

      Volume: 113 Pages: 711-712

    • URL

      http://dx.doi.org/10.1016/j.oooo.2012.02.008

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Journal Article] Effects of unilateral jaw clenching on cerebral/systemic circulation and related autonomic nerve activity2012

    • Author(s)
      Zhang M, Hasegawa Y, Sakagami J, Ono T, Hori K, Maeda Y, Chen YJ.
    • Journal Title

      Physiology & Behavior

      Volume: 105 Pages: 292-297

    • URL

      http://www.sciencedirect.com/science/article/pii/S0031938411003805

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Movement of the mandibular condyle and articular disc on placement of an occlusal splint2011

    • Author(s)
      Hasegawa Y, Kakimoto N, Tomita S,et al
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod

      Volume: 112 Pages: 640-647

    • URL

      http://dx.doi.org/10.1016/j.tripleo.2011.06.013

    • Related Report
      2012 Final Research Report
  • [Journal Article] Movement of the mandibular condyle and articular disc on placement of an occlusal splint2011

    • Author(s)
      Hasegawa Y, Kakimoto N, Tomita S, Honda K, Tanaka Y, Yagi K, Kondo J, Nagashima T, Ono T, Maeda Y.
    • Journal Title

      Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

      Volume: 112 Pages: 640-647

    • URL

      http://www.sciencedirect.com/science/article/pii/S1079210411004136

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 味および香りがガム咀嚼時のストレスに及ぼす影響2012

    • Author(s)
      長谷川陽子,橘吉寿,小野高裕.
    • Organizer
      第23回日本咀嚼学会学術大会・総会.
    • Place of Presentation
      北海道
    • Year and Date
      2012-10-13
    • Related Report
      2012 Final Research Report
  • [Presentation] オクルーザルスプリントによる顎関節の変位が顎関節部の痛みに及ぼす影響2012

    • Author(s)
      長谷川陽子,柿本直也,富田世紀,本田公亮,田中裕人,小野高裕,藤原正識,前田芳信
    • Organizer
      日本補綴歯科学会平成23年度関西支部学術大会.
    • Place of Presentation
      神戸
    • Year and Date
      2012-02-13
    • Related Report
      2012 Final Research Report
  • [Presentation] 味および香りがガム咀嚼時のストレスに及ぼす影響2012

    • Author(s)
      長谷川陽子
    • Organizer
      第23回日本咀嚼学会学術大会・総会
    • Place of Presentation
      札幌
    • Related Report
      2012 Annual Research Report
  • [Presentation] オクルーザルスプリントによる顎関節の変位が顎関節部の痛みに及ぼす影響2012

    • Author(s)
      長谷川陽子,柿本直也,富田世紀,本田公亮,田中佑人,小野高裕,藤原正識,前田芳信
    • Organizer
      日本補綴歯科学会関西支部会
    • Place of Presentation
      神戸
    • Related Report
      2011 Research-status Report
  • [Presentation] 習慣性咀嚼側が脳循環に及ぼす影響2011

    • Author(s)
      長谷川陽子,阪上穣,小野高裕,堀一浩,本田公亮,浦出雅裕.
    • Organizer
      日本顎口腔機能学会第47回学術大会.
    • Place of Presentation
      神戸
    • Year and Date
      2011-10-22
    • Related Report
      2012 Final Research Report
  • [Presentation] Influence of Denture Wearing on Outcome of Treatment for Bisphosphonate-Related Osteonecrosis of the Jaws.Nationwide Survey in Japan2011

    • Author(s)
      Hasegawa Y, Kawabe M, Kimura H, Kurita K, Fukuda J, Urade M.
    • Organizer
      14th Meeting of the International College of Prosthodontists.
    • Place of Presentation
      Hawaii, USA
    • Year and Date
      2011-09-09
    • Related Report
      2012 Final Research Report
  • [Presentation] Influence of an occlusal splint on TMJ position2011

    • Author(s)
      Hasegawa Y, Kakimoto N, Tomita S,Tanaka Y, Yagi K, Nagashima T, Honda K, Ono T, Kondo J, Maeda Y, Urade M.
    • Organizer
      IADR 89th General Session and Exhibition.
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 習慣性咀嚼側が脳循環に及ぼす影響2011

    • Author(s)
      長谷川陽子,阪上穣,小野高裕,堀一浩,本田公亮,浦出雅裕
    • Organizer
      顎口腔機能学会
    • Place of Presentation
      神戸
    • Related Report
      2011 Research-status Report
  • [Presentation] Influence of Denture Wearing on Outcome of Treatment for Bisphosphonate-Related Osteonecrosis of the Jaws2011

    • Author(s)
      Hasegawa Y, Kawabe M, Kimura H, Kurita K, Fukuda J, Urade M
    • Organizer
      2011 international college of prosthodontists meeting
    • Place of Presentation
      ハワイ島
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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