| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
We examined whether combined therapy of fibroblast growth factor 2 (FGF-2) induced wound healing and collagen hydrogel scaffold stimulated periodontal regeneration. Collagen hydrogel scaffold has rapid cell infiltration in the scaffold and replacement by regenerative tissue with low cytotoxicity. Implantation of collagen hydrogel scaffold in combination with FGF-2 enhanced regeneration of alveolar bone, cementum, periodontal ligament in beagle dogs. The combined therapy is expected to be a suitable therapy for periodontal tissue engineering.
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