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Pioneering research of the effect of Bisphosphonate to achieved osseointegrated implants

Research Project

Project/Area Number 23792278
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionOsaka University

Principal Investigator

WADA Masahiro  大阪大学, 大学院・歯学研究科, 助教 (20452451)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords歯科インプラント / ビスフォスフォネート製剤 / ビスフォスフォネート / インプラント
Research Abstract

After establish the ossointegration model with rat, examine about the effect of Bisphosphonate (BP) to this model. In result, removable torque was increased by administration of BP at immediately after administration of BP and 3 month later. On the otherhand, Bone resorption marker : NTX was decreased at the immediately after administration of BP, and was increased at the 3 month. Therefore, administration of BP affect the bone kinetic around the osseointegrated implant.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2012

All Presentation (2 results)

  • [Presentation] 骨代謝マーカーを用いたオッセオインテグレーション過程における骨動態の検討2012

    • Author(s)
      和田誠大
    • Organizer
      第121回日本補綴歯科学会
    • Place of Presentation
      神奈川県民ホール
    • Related Report
      2012 Final Research Report
  • [Presentation] 骨代謝マーカーを用いたオッセオインテグレーション過程における骨動態の検討2012

    • Author(s)
      和田誠大
    • Organizer
      日本補綴歯科学会
    • Place of Presentation
      神奈川県民ホール
    • Related Report
      2012 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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