Prospective isolation and investigation of human dental pulp stemcells by using specific cell surface markers

• Project/Area Number: 23792293
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Dental engineering/Regenerative dentistry
• Research Institution: Keio University
• Principal Investigator: YASUI Takazumi 慶應義塾大学, 医学部, 共同研究員 (80348771)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 再生医療 / 歯髄幹細胞 / 細胞表面マーカー / フローサイトメトリー

Research Abstract

Traditionally, human dental pulp stem cells (hDPSCs) isolated by plastic adherence,frequently contain contaminating mature cells, which has limited our ability to investigatetheir basic biology and regenerative properties. In the present study, we identif

Research Products

• [Presentation] Prospective Isolation of Human DentalPulp Stem Cells (2013)
  • Author(s): Takazumi Yasui, Yo Mabuchi, Haruki Toriumi,Daisuke Araki, Kunimichi Niibe, SatoruMorikawa, Takeshi Karube, KatsuhiroOnizawa, Hiromasa Kawana, Yutaka Tomita,Norihiro Suzuki, Taneaki Nakagawa,Hideyuki Okano and Yumi Matsuzaki
  • Organizer: 91st General Session & Exhibition of theIADR(International Association for DentalResearch)
  • Place of Presentation: シアトル
  • Year and Date: 2013-03-23
• [Presentation] Prospective Isolation of Human Dental Pulp Stem Cells (2013)
  • Author(s): Takazumi Yasui
  • Organizer: 91st General Session & Exhibition of the IADR
  • Place of Presentation: シアトル
• [Presentation] FACS を用いたヒト歯髄幹細胞の予期的分離法 (2012)
  • Author(s): 安居孝純, 鬼澤勝弘,軽部健史, 森川 暁,河奈裕正, 中川種昭
  • Organizer: 第57回日本口腔外科学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2012-10-21
• [Presentation] FACS を用いたヒト歯髄幹細胞の予期的分離法 (2012)
  • Author(s): 安居孝純,馬渕 洋, 鬼澤勝弘, 中川種昭,岡野栄之, 松崎有未
  • Organizer: 第11回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2012-10-21
• [Presentation] FACSを用いたヒト歯髄幹細胞の予期的分離法 (2012)
  • Author(s): 安居孝純
  • Organizer: 第11回日本再生医療学会総会
  • Place of Presentation: 横浜
• [Presentation] FACSを用いたヒト歯髄幹細胞の予期的分離法 (2012)
  • Author(s): 安居孝純
  • Organizer: 第57回日本口腔外科学会総会
  • Place of Presentation: 横浜
• [Presentation] 抗VEGFモノクロナール抗体ベバシズマブの関与が疑われた顎骨壊死の1例 (2011)
  • Author(s): 安居孝純、鬼澤勝弘、蔭山雄基、兵藤朋子、岩崎良太郎、莇生田整治
  • Organizer: 第56回日本口腔外科学会総会
  • Place of Presentation: 大阪国際会議場（大阪府）
• [Remarks]
  • URL: http://dent-os.med.keio.ac.jp/KEIO/classroom/record/