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Elucidation of trouble circulation mechanism caused by Diabetic autonomic neuropathy

Research Project

Project/Area Number 23792335
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionOsaka University

Principal Investigator

BOKU Aiji  大阪大学, 歯学研究科, 助教 (50587566)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords歯科麻酔学 / 糖尿病 / 出血 / 自律神経 / c-Fos
Research Abstract

In the diabetic rat, I observed the onset of the c-Fos positivity cellular in the rachidian-bulb solitary nucleus Intra Medial on the occasion of an acute hemorrhage. This was the same pattern of manifestation as the time of prescribing a phenylephrine for a control rat, and making a baroreceptor reflex induce.As mentioned above, in the diabetic rat,it became clear that the vagus was involving deeply in the phenomenon which the Bezold-Jarisch reflex rose at the time of an acute hemorrhage and the compensatory mechanism over a staxis fails at an early stage.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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