| Project/Area Number |
23792350
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
|
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| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
TAKAISHI Kazumi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (20325286)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
AKI Kenji 徳島文理大学, 研究科学研究所, 教授 (20035405)
KITAHATA Hirsohi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (60161486)
|
|---|
| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 歯科麻酔学 / 鉄イオン / フェリチン / 還元 / 局所麻酔薬 / 還元物質 |
|---|
| Research Abstract |
Nucleotide-dependent flavoenzyme (NADPH-p450 reductase) mobilized reductively iron from ferritin. In cultured bovine aortic endothelial cells, lidocaine and procaine, local anesthetics, inhibited the activity of nitric oxide synthase which is one of reducing agents of iron.
|
