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Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells

Research Project

Project/Area Number 23792399
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionHyogo Medical University

Principal Investigator

SEGAWA Emi  兵庫医科大学, 医学部, 研究生(研究員) (00553778)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordszyxin / Zyxin
Research Abstract

Zyxin is an evolutionarily conserved protein that has been implicated in the regulation of actin assembly and is mainly located at focal adhesions. However, the biological roles of Zyxin in cancer cells are incompletely understood. We analyzed the functions of Zyxin in cell migration and the invasive potential of OSCC

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (3 results)

All 2013 2011

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells.2013

    • Author(s)
      Yamamura M, Noguchi K, Nakano Y, Segawa E at al.
    • Journal Title

      Int J Oncol

      Volume: 42(3) Issue: 3 Pages: 873-80

    • DOI

      10.3892/ijo.2013.1761

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Presentation] 口腔扁平上皮癌細胞におけるEMTmakerとしてのZyxinの発現2011

    • Author(s)
      瀬川英美
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Year and Date
      2011-10-05
    • Related Report
      2012 Final Research Report
  • [Presentation] 口腔扁平上皮癌細胞におけるEMTmakerとしてのZyxinの発現2011

    • Author(s)
      瀬川英美
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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