| Project/Area Number |
23792413
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
MIYAJIMA Yuki 東北大学, 大学院・歯学研究科, 大学院非常勤講師 (30583372)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 歯科矯正学 / 金属ガラス / 生体材料 / 矯正用ミニスクリュー |
|---|
| Research Abstract |
In this study, in order to evaluate the usefulness of Zr70Ni16Cu6Al8 bulk metallic glasses(Zr-BMG) as a mini-screw for the orthodontic treatment, we analyzed from biological viewpoint. As a result, since bone-marrow mesenchymal cells on the Zr-BMG have the potential of focal adhesion, proliferation and osteogenic differentiation when cultured by osteogenic induction medium in vitro, it became clear that Zr-BMG have good biocompatibility. And more, we transplanted the Zr-BMG into the rat maxillary jaw. No inflammatory responses were seen in vivo.
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