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Development of the orthodontic mini-screw made by bulk metallic glasses

Research Project

Project/Area Number 23792413
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Orthodontic/Pediatric dentistry
Research InstitutionTohoku University

Principal Investigator

MIYAJIMA Yuki  東北大学, 大学院・歯学研究科, 大学院非常勤講師 (30583372)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Keywords歯科矯正学 / 金属ガラス / 生体材料 / 矯正用ミニスクリュー
Research Abstract

In this study, in order to evaluate the usefulness of Zr70Ni16Cu6Al8 bulk metallic glasses(Zr-BMG) as a mini-screw for the orthodontic treatment, we analyzed from biological viewpoint. As a result, since bone-marrow mesenchymal cells on the Zr-BMG have the potential of focal adhesion, proliferation and osteogenic differentiation when cultured by osteogenic induction medium in vitro, it became clear that Zr-BMG have good biocompatibility. And more, we transplanted the Zr-BMG into the rat maxillary jaw. No inflammatory responses were seen in vivo.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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