Development of rapid diagnostic device for periodontal diseaseusing microchip

• Project/Area Number: 23792494
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Periodontal dentistry
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: ABE Kaori 独立行政法人産業技術総合研究所, 健康工学研究部門, 産総研特別研究員 (60511326)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
• Keywords: マイクロチップ / 炎症性サイトカイン / 診断 / 歯周病

Research Abstract

In the conventional sandwich enzyme-linked immunosorbant assay (ELISA) system, disposable 96-well microtitration plates are frequently employed to detect inflammatory cytokines in blood. Typically 50～100 μl aliquots of sample are introduced into the react

Research Products

• [Journal Article] Simultaneous immunoassay analysis of plasma IL-6 and TNF-α on a microchip (2013)
  • Author(s): Abe K, Hashimoto Y, Yatsushiro S, Yamamura S, Bando M, Hiroshima Y, Kido J, Tanaka M, Shinohara Y, Ooie T, Baba Y, Kataoka M
  • Journal Title: PLoS One Volume: 8 Issue: 1 Pages: e53620-e53620
  • DOI: 10.1371/journal.pone.0053620
  • Peer Reviewed
• [Journal Article] Quantitative analysis of plasma interleiukin-6 by immunoassay on microchip (2012)
  • Author(s): Kaori Abe
  • Journal Title: Journal of Physics : Conference Series Volume: 352 Pages: 0120441-5
  • DOI: 10.1088/1742-6596/352/1/012044
  • Peer Reviewed
• [Presentation] マイクロチップ基板を用いた血中サイトカインの迅速検出法の構築 (2012)
  • Author(s): 阿部佳織
  • Organizer: 第55回春季歯周病学会学術大会
  • Place of Presentation: 札幌コンベンションセンター(北海道)
  • Year and Date: 2012-05-18
• [Presentation] Quantitative analysis of serum interleukin-6 by immunoassay on microchip (2011)
  • Author(s): Kaori Abe
  • Organizer: The Asia-Pacific Interdisciplinary Research Conference 2011
  • Place of Presentation: 愛知県 豊橋技術科学大学
• [Presentation] マイクロチップ基板を用いた血中サイトカインの迅速検出法の構築
  • Author(s): 阿部佳織
  • Organizer: 第55回春季日本歯周病学会学術大会
  • Place of Presentation: 札幌