Inhibition of swallowing during chewing
| Project/Area Number |
23792507
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 生理学 / 嚥下 / 咀嚼 / 上喉頭神経 / 皮質咀嚼野 / ラット |
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| Research Abstract |
To clarify the neural mechanism of swallowing inhibition during chewing, we investigated the effect of electrical stimulation of two cortical masticatory areas (A- and P-area) on superior laryngeal nerve-evoked swallows. The number of evoked swallows was significantly lower during A-area stimulation. Conversely, swallowing reflexes were not changed by P-area stimulation. The inhibition of swallows by A-area stimulation was notaffected by an increase in sensory input facilitated by wooden stick application between upper and lower teeth, or A-area stimulation preceding SLN stimulation. We speculate that swallowing inhibition may be mediated by direct inputs from the A-are or inputs via the masticatory center into the swallowing center.
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Report
(3 results)
Research Products
(13 results)
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[Journal Article] Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis, upper cervical cord, NTS and Pa5 following capsaicin injection into masticatory and swallowing-related muscles in rats2011
Author(s)
Tsujimura T, Shinoda M, Honda K, Hitomi S, Kiyomoto M, Matsuura S, Katagiri A, Tsuji K, Inoue M, Shiga Y, Iwata K
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Journal Title
Brain Res
Volume: 1417
Pages: 45-54
Related Report
Peer Reviewed
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