• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Inhibition of swallowing during chewing

Research Project

Project/Area Number 23792507
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Social dentistry
Research InstitutionNiigata University

Principal Investigator

TSUJIMURA Takanori  新潟大学, 医歯学系, 助教 (00548935)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords生理学 / 嚥下 / 咀嚼 / 上喉頭神経 / 皮質咀嚼野 / ラット
Research Abstract

To clarify the neural mechanism of swallowing inhibition during chewing, we investigated the effect of electrical stimulation of two cortical masticatory areas (A- and P-area) on superior laryngeal nerve-evoked swallows. The number of evoked swallows was significantly lower during A-area stimulation. Conversely, swallowing reflexes were not changed by P-area stimulation. The inhibition of swallows by A-area stimulation was notaffected by an increase in sensory input facilitated by wooden stick application between upper and lower teeth, or A-area stimulation preceding SLN stimulation. We speculate that swallowing inhibition may be mediated by direct inputs from the A-are or inputs via the masticatory center into the swallowing center.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Research-status Report
  • Research Products

    (13 results)

All 2012 2011

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (9 results)

  • [Journal Article] Differential involvement of two cortical masticatory areas in modulation of the swallowing reflex in rats2012

    • Author(s)
      Tsujimura T, Tsuji K, Ariyasinghe S, Fukuhara T, Yamada A, Hayashi H, Nakamura Y, Iwata K, Inoue M
    • Journal Title

      Neurosci Lett

      Volume: 528(2) Pages: 159-64

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential involvement of two cortical masticatory areas in modulation of the swallowing reflex in rats2012

    • Author(s)
      T Tsujimura, K Tsuji, S Ariyasinghe, T Fukuhara, A Yamada, H Hayashi, Y Nakamura, K Iwata, M Inoue
    • Journal Title

      Neurosci Lett

      Volume: 528(2) Issue: 2 Pages: 159-164

    • DOI

      10.1016/j.neulet.2012.09.005

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis, upper cervical cord, NTS and Pa5 following capsaicin injection into masticatory and swallowing-related muscles in rats2011

    • Author(s)
      Tsujimura T, Shinoda M, Honda K, Hitomi S, Kiyomoto M, Matsuura S, Katagiri A, Tsuji K, Inoue M, Shiga Y, Iwata K
    • Journal Title

      Brain Res

      Volume: 1417 Pages: 45-54

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Organization of pERK-immunoreactive cells in trigeminal spinal nucleus caudalis, upper cervical cord, NTS and Pa5 following capsaicin injection into masticatory and swallowing-related muscles in rats2011

    • Author(s)
      Takanori Tsujimura
    • Journal Title

      Brain Research

      Volume: 1417 Pages: 45-54

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] 上喉頭神経および皮質誘発嚥下に対する皮質咀嚼野刺激の変調効果2012

    • Author(s)
      辻村恭憲,辻光順,岩田幸一,井誠
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] Differential involvements of two cortical masticatory areas in modulation of superior laryngeal nerve-evoked swallows in rats2012

    • Author(s)
      Tsujimura T, Tsuji K, Iwata K, Inoue M
    • Organizer
      Dysphagia Research Society 19th Annual Meeting
    • Place of Presentation
      Toronto, Canada
    • Related Report
      2012 Final Research Report
  • [Presentation] Differential involvements of two cortical masticatory areas in modulation of superior laryngeal nerve-evoked swallows in rats2012

    • Author(s)
      Takanori Tsujimura
    • Organizer
      Dysphagia Research Society 20th Annual Meeting
    • Place of Presentation
      The Ritz-Carlton (Toronto)
    • Related Report
      2011 Research-status Report
  • [Presentation] ラット上喉頭神経誘発嚥下に対する皮質咀嚼野刺激の変調効果2011

    • Author(s)
      辻村恭憲,辻光順,岩田幸一,井上誠
    • Organizer
      第5回三叉神経領域の感覚-運動統合機構研究会
    • Place of Presentation
      長野
    • Related Report
      2012 Final Research Report
  • [Presentation] Differential involvement of two cortical masticatory areas in SLN-evoked swallows in rats2011

    • Author(s)
      Tsujimura T, Fukuhara T, Yamada A, Nakamura Y, Kajii Y, Iwata K, Inoue M
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      Washington DC,USA
    • Related Report
      2012 Final Research Report
  • [Presentation] 上喉頭神経誘発嚥下に対する2つの皮質咀嚼野刺激の異なる変調効果2011

    • Author(s)
      辻村恭憲,福原孝子,山田亜紀,中村由紀,岩田幸一,井上誠
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Related Report
      2012 Final Research Report
  • [Presentation] ラット上喉頭神経誘発嚥下に対する皮質咀嚼野刺激の変調効果2011

    • Author(s)
      辻村恭憲
    • Organizer
      第5回三叉神経領域の感覚―運動統合機構研究会
    • Place of Presentation
      高原の宿スカイランド きよみず (長野)
    • Related Report
      2011 Research-status Report
  • [Presentation] Differential involvement of two cortical masticatory areas in SLN-evoked swallows in rats2011

    • Author(s)
      Takanori Tsujimura
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      the Walter E Washington Convention Center (Washington DC)
    • Related Report
      2011 Research-status Report
  • [Presentation] 上喉頭神経誘発嚥下に対する2つの皮質咀嚼野刺激の異なる変調効果,2011

    • Author(s)
      辻村恭憲
    • Organizer
      第53回歯科基礎医学会学術大会
    • Place of Presentation
      長良川国際会議場 (岐阜)
    • Related Report
      2011 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi