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Establishment of the remineralization-promoting treatment and the caries-preventive protocol by novel fissure sealant

Research Project

Project/Area Number 23792525
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Social dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

SHIMAZU Kisaki  日本歯科大学, 生命歯学部, 講師 (80582254)

Project Period (FY) 2011-04-28 – 2013-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsシーラント / S-PRGフィラー / フッ素リリース・リチャージ / イオン徐放 / 脱灰・再石灰化 / 齲蝕予防 / 歯科材料
Research Abstract

We aimed to evaluate the caries-preventive effect of a fissure sealant containing surface reaction-type pre-reacted glass ionomer (S-PRG) filler. For the sealant containing S-PRG filler, high amount of Sr and B ions was detected, and a considerable amount of fluoride was released after a recharge with a high concentration of fluoride. Moreover, the S-PRG filler-containing sealant bonded by self-etching primer maintained the enamel surface integrity and inhibited enamel demineralization. In addition, the sealant had a higher bond strength on both untreated enamel and enamel subsurface lesions than the conventional resin-based sealants bonded by acid etching. These findings suggest that sealants containing S-PRG filler enhance the enamel demineralization-inhibiting effect and the remineralization-promoting effect for long-term dental care.

Report

(3 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • Research Products

    (27 results)

All 2014 2013 2012 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (17 results) (of which Invited: 1 results) Remarks (3 results)

  • [Journal Article] S-PRGフィラー含有シーラントの齲蝕予防効果の検討2013

    • Author(s)
      島津貴咲
    • Journal Title

      小児歯誌

      Volume: 52(3) Pages: 347-352

    • NAID

      10030558603

    • URL

      http://www.jspd.or.jp/contents/gakkai/journal/j_journal.html

    • Related Report
      2013 Final Research Report
  • [Journal Article] Evaluation of the caries-preventive effect of three orthodontic band cements in terms of fluoride release, retentiveness, and microleakage2013

    • Author(s)
      Shimazu K, Ogata K, Karibe H
    • Journal Title

      Dental Materials Journal

      Volume: 32 Issue: 3 Pages: 376-380

    • DOI

      10.4012/dmj.2012-283

    • NAID

      10031158835

    • ISSN
      0287-4547, 1881-1361
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the caries-preventive effect of three orthodontic band cements in terms of fluoride release, retentiveness, and microleakage2013

    • Author(s)
      Kisaki SHIMAZU, Kiyokazu OGATA, and Hiroyuki KARIBE
    • Journal Title

      Dental Materials Journal

      Volume: 32(3) Pages: 376-380

    • NAID

      10031158835

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] S-PRGフィラー含有シーラントの齲蝕予防効果の検討2013

    • Author(s)
      島津貴咲
    • Journal Title

      小児歯科学雑誌

      Volume: 51(3) Pages: 347-352

    • NAID

      10030558603

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Evaluation of the caries-preventive effect of three orthodontic band cements in2013

    • Author(s)
      Kisaki SHIMAZU, Kiyokazu OGATA, Hiroyuki KARIBE
    • Journal Title

      Dental Materials Journal

      Volume: 32(2) Pages: 1-5

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Caries-preventive effect of fissure sealant containing surface reaction-type pre-reacted glass ionomer filler and bonded by self-etching primer2012

    • Author(s)
      Shimazu K, Ogata K, Karibe H
    • Journal Title

      J Clin Pediatr Dent

      Volume: 36(4) Pages: 343-347

    • URL

      http://pediatricdentistry.metapress.com/home/main.mpx

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Caries-Preventive Effect of Fissure Sealant Containing SurfaceReaction-Type Pre-reacted Glass Ionomer Filler and Bonded by Self-etching Primer2012

    • Author(s)
      Shimazu K, Ogata K, Karibe H
    • Journal Title

      The Journal of Clinical Pediatric Dentistry

      Volume: 36(4) Pages: 343-347

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] S-PRG溶出液の口腔微生物に対する抗菌効果2014

    • Author(s)
      島津貴咲,高橋幸裕,小口莉代,古西清司,苅部洋行
    • Organizer
      第52回日本小児歯科学会
    • Place of Presentation
      東京,品川区立総合区民会館
    • Related Report
      2013 Final Research Report
  • [Presentation] S-PRG溶出液の口腔微生物に対する抗菌効果2014

    • Author(s)
      島津貴咲,高橋幸裕,小口莉代,古西清司,苅部洋行
    • Organizer
      第52回日本小児歯科学会
    • Place of Presentation
      東京,品川区立総合区民会館
    • Related Report
      2013 Annual Research Report
  • [Presentation] 歯磨きによる唾液酸緩衝能の変化2013

    • Author(s)
      横山美世子,朝倉美希,大野智,角掛愛,中村元一,巻祐太,水沼詩葉,加藤雄一,島津貴咲
    • Organizer
      第28回日本小児歯科学会関東地方会大会・総会
    • Place of Presentation
      神奈川,神奈川歯科大学
    • Year and Date
      2013-10-27
    • Related Report
      2013 Final Research Report
  • [Presentation] Evaluation of the caries-preventive effect of three orthodontic band cements2013

    • Author(s)
      Shimazu K, Ogata K, Karibe H
    • Organizer
      92th International Association for Dental Research
    • Place of Presentation
      Washington State Convention Center 800, Seattle, Washington, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] サーマルサイクル負荷による各種バンド用セメントの微小漏洩の評価2013

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      第51回日本小児歯科学会
    • Place of Presentation
      岐阜,長良川国際会議場
    • Related Report
      2013 Annual Research Report
  • [Presentation] 充填材料の接着における唾液混入の影響2013

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      2013年度日本歯科保存学会春季学術大会(第138回)
    • Place of Presentation
      福岡,福岡国際会議場
    • Related Report
      2013 Annual Research Report
  • [Presentation] Evaluation of the caries-preventive effect of three orthodontic band cements2013

    • Author(s)
      Shimazu K, Ogata K, Karibe H
    • Organizer
      International Association for Dental Research
    • Place of Presentation
      Washington State Convention Center, 800. Seattle, Washington, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] サーマルサイクル負荷による各種バンド用セメントの微小漏洩の評価2013

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      第51回 日本小児歯科学会
    • Place of Presentation
      岐阜、長良川国際会議場
    • Related Report
      2012 Research-status Report
  • [Presentation] 充填材料の接着における唾液混入の影響2013

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      第138回 日本歯科保存学会春季大会
    • Place of Presentation
      福岡、福岡国際会議場
    • Related Report
      2012 Research-status Report
  • [Presentation] S-PRGフィラー含有シーラントの齲蝕予防効果の検討2012

    • Author(s)
      島津貴咲
    • Organizer
      第50回日本小児歯科学会,学術賞・奨励賞受賞講演
    • Place of Presentation
      東京,東京国際フォーラム
    • Year and Date
      2012-05-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Caries-preventive effect of novel resin-based fissure sealant2012

    • Author(s)
      Karibe H, Shimazu K, Ogata K
    • Organizer
      65th annual session of American Academy of Pediatric Dentistry
    • Place of Presentation
      San Diego Convention Center, San Diego, California, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] 新規S-PRGフィラー含有シーラントの有用性フッ素リリース能とリチャージ能の評価2012

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      第50回日本小児歯科学会
    • Place of Presentation
      東京,東京国際フォーラム
    • Related Report
      2013 Final Research Report
  • [Presentation] S-PRGフィラー含有シーラントの齲蝕予防効果の検討2012

    • Author(s)
      島津貴咲
    • Organizer
      第50回 日本小児歯科学会,学術賞・奨励賞受賞講演
    • Place of Presentation
      東京、東京国際フォーラム
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] 新規S-PRGフィラー含有シーラントの有用性 フッ素リリース能とリチャージ能の評価2012

    • Author(s)
      島津貴咲,小方清和,苅部洋行
    • Organizer
      第50回 日本小児歯科学会
    • Place of Presentation
      東京、東京国際フォーラム
    • Related Report
      2012 Research-status Report
  • [Presentation] 齲蝕予防と操作性を考慮したバンド用合着材の検討2012

    • Author(s)
      小方清和,島津貴咲,苅部洋行
    • Organizer
      第50回 日本小児歯科学会
    • Place of Presentation
      東京、東京国際フォーラム
    • Related Report
      2012 Research-status Report
  • [Presentation] Caries-preventive effect of novel resin-based fissure sealant2012

    • Author(s)
      Karibe H, Shimazu K, Ogata K
    • Organizer
      65th annual session of American Academy of Pediatric Dentistry
    • Place of Presentation
      San Diego Convention Center. San Diego, California, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] 歯磨きによる唾液酸緩衝能の変化

    • Author(s)
      横山美世子,朝倉美希,大野智,角掛愛,中村元一,巻祐太,水沼詩葉,加藤雄一,島津貴咲
    • Organizer
      第28回日本小児歯科学会関東地方会大会
    • Place of Presentation
      神奈川,神奈川歯科大学
    • Related Report
      2013 Annual Research Report
  • [Remarks] 日本歯科大学生命歯学部小児歯科学講座 ホームページ

    • URL

      http://www.ndu.ac.jp/~pedo/index.html

    • Related Report
      2013 Final Research Report
  • [Remarks] 日本歯科大学生命歯学部小児歯科学講座ホームページ

    • URL

      http://www.ndu.ac.jp/~pedo/index.html

    • Related Report
      2013 Annual Research Report
  • [Remarks] 日本歯科大学生命歯学部小児歯科学講座ホームページ

    • URL

      http://www.ndu.ac.jp/~pedo/index.html

    • Related Report
      2012 Research-status Report

URL: 

Published: 2011-08-05   Modified: 2019-07-29  

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