The effects of the degradation of mucin by Streptococci on the mechanism of oral malodor
| Project/Area Number |
23792532
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
TANIGUCHI NAO 福岡歯科大学, 歯学部, 講師 (60372885)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 揮発性硫黄化合物 / 口腔内細菌叢 / 口臭 / 高速シーケンス解析 / グルコシダーゼ / 唾液 / β-galactosidase / βガラクトシダーゼ / 舌苔 / 口腔内細菌 / galactosidase / volatile sulfur compound / halitosis / oral streptococci / physiologic halitosis |
|---|
| Research Abstract |
Salivary beta-galactosidase activity from the patients complaining of halitosis was measured and compared between the periodontally healthy group and the periodontitis group. Positive correlations were observed between the beta-galactosidase activity and oral malodor levels in the periodontally healthy group. Concerning the clinical parameter, the plaque index and tongue coating score were positively correlated with beta-galactosidase activity in the periodontal healthy group. Next, the bacterial compositions of saliva exhibiting higher and lower malodor were explored in order to determine the specific microbial community related to oral malodor. In addition, the compositions of oral microbiota associated with high hydrogen sulfide and methyl mercaptan production were determined. Tongue coating is main sources of oral malodor, and therefore the beta-galactosidase activity of tongue coating was measured.
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Report
(4 results)
Research Products
(61 results)
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[Journal Article] Lactobacillus salivarius WB21-containing tablets for the treatment of oral malodor: a double-blind, randomized, placebo-controlled crossover trial.2014
Author(s)
Suzuki N, Yoneda M, Tanabe K, Fujimoto A, Iha K, Seno K, Yamada K, Iwamoto T, Masuo Y, Hirofuji T
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Journal Title
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology
Volume: 117
Issue: 4
Pages: 462-470
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Association between oral malodour and psychological characteristics in subjects with neurotic tendencies complaining of halitosis.2011
Author(s)
Suzuki N, Yoneda M, Naito T, Inamitsu T, Yamada K, Okada I, Hatano Y, Iwamoto T, Masuo Y, Fuijimoto A, Hirofuji T.
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Journal Title
International of Dental Journal
Volume: 61
Issue: 2
Pages: 57-62
DOI
Related Report
Peer Reviewed
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[Presentation] Improvement of oral malodor using Lactobacillus salivarius WB21-containing tablets2013
Author(s)
Suzuki N, Yoneda M, Tanabe K, Fujimoto A, Iha K, Seno K, Iwamoto T, Yamada K, Masuo Y, Haruna K, and Hirofuji T
Organizer
WCPD
Place of Presentation
Budapest
Related Report
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[Presentation] Improvement of oral malodor using Lactobacillus salivarius WB21-containing tablets.2013
Author(s)
Suzuki N, Yoneda M, Tanabe K, Fujimoto A, Iha K, Seno K, Iwamoto T, Yamada K, Masuo Y, Haruna K, and Hirofuji T.
Organizer
WCPD
Place of Presentation
Budapest
Related Report
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[Presentation] ヒノキチオール配合ジェルを用いた口腔ケアの口臭改善効果2013
Author(s)
伊波幸作、鈴木奈央、米田雅裕, 山田和彦, 岩元知之, 桝尾陽介, 藤本暁江, 瀬野恵衣, 春名一人, 安 忠大, 入江丹佳子, 西原哲世, 仲西宏介, 廣藤卓雄
Organizer
総合歯科協議会
Place of Presentation
東京
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