Stress Management Ability of Patients with Inflammatory Bowel Disease and Effects of Intervention for Them: A Basic Study
| Project/Area Number |
23792592
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical nursing
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| Research Institution | Saga University |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 慢性病看護学 / 下部消化管学 / サイトカイン |
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| Outline of Final Research Achievements |
A questionnaire survey with blood sampling was conducted, involving patients with Crohn’s disease (CD) or ulcerative colitis (UC) and healthy individuals. Compared to healthy individuals, patients with CD and UC showed lower self-efficacy and higher IL-6 and cortisol levels. In those with CD, increased CRF, TNF-α, and serotonin levels were also observed. Measurement of personality traits revealed a tendency of both patients with CD and UC to face difficulty in expressing their emotions and develop a sense of inferiority; the former also exhibited reasonable behavior. These results suggest the possibility of patients with CD and UC facing difficulty in managing stress due to impaired nervous, endocrine, and immune systems. Although the effects of intervention were not fully clarified in this study, cognitive behavioral therapy, such as assertiveness training and approaches to address cognitive distortions, is likely to be effective.
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Report
(5 results)
Research Products
(4 results)
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[Journal Article] Chemopreventive effect of mofezolac on beef tallow diet/azoxymethane-induced colon carcinogenesis in rats.2011
Author(s)
Miao L, Shiraishi R, Fujise T, Kuroki T, Kakimoto T, Sakata Y, Takashima T, Iwakiri R, Fujimoto K, Shi R, Li X.
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Journal Title
Hepatogastroenterology
Volume: 58(105)
Pages: 81-88
Related Report
Peer Reviewed
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