Association between Helicobacter pylori infection with atrophic gastritis and lifestyle: a general population-based cohort study

• Project/Area Number: 23792684
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Community health/Gerontological nurisng
• Research Institution: Hirosaki University
• Principal Investigator: KURAUCHI Shizuka 弘前大学, 保健学研究科, 助教 (60455730)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: ヘリコバクター・ピロリ感染 / 萎縮性胃炎 / 生活習慣

Research Abstract

An association between incidence of stomach cancer and Helicobacter pylori (Hp)-induced atrophic gastritis (AG) has been reported in a number of previous studies. In this Japanese general population-based study, we examined the relationship between Hp infection with AG and lifestyle. Subjects included participants from a health promotion project who were infected with Hp without AG in 2007 (n=41). They were divided into the maintenance group (AG(-), n=35) and the progression group (AG(+), n=6) according to the AG state in 2012. In many maintenance group, there were many subjects who underwent with eradication therapy of Hp, which could prevent progression of AG. No significant differences were seen between groups in lifestyle data; however, significant differences were evident in dietary intake of milk and fish with less fat in the previous month. Relationships between food and mucosal atrophy should be examined for gastric cancer prevention.

Research Products

• [Journal Article] Association Between Helicobacter Pylori Infection And Atrophic Gastritis, and Serum Selenium Concentration (2012)
  • Author(s): Shizuka Kurauchi, Ippei Takahashi, Masashi Matsuzaka, Kaori Iwane, Kazuma Danjo, Mariko Semato, Manabu Hamano, Terumi Kogawa, Takashi Umeda, Shigeyuki Nakaji
  • Journal Title: The Hirosaki Medical Journal Volume: 63 Pages: 105-115
  • NAID: 110009550205
  • URL: http://repository.ul.hirosaki-u.ac.jp:8080/dspace/bitstream/10129/4812/1/HirosakiMedJ_63%282-4%29_105.pdf
  • Peer Reviewed
• [Journal Article] ASSOCIATION BETWEEN HELICOBACTER PYLORI INFECTION AND ATROPHIC GASTRITIS, AND SERUM SELENIUM CONCENTRATION (2012)
  • Author(s): Shizuka Kurauchi, Ippei Takahashi, Masashi Matsuzaka, Kaori Iwane, Kazuma Danjo, Mariko Semato, Manabu Hamano, Terumi Kogawa, Takashi Umeda, Shigeyuki Nakaji
  • Journal Title: THE HIROSAKI MEDICAL JOURNAL Volume: 63 Pages: 105-115
  • NAID: 110009550205
  • Peer Reviewed