Design and Fabrication of Dynamic DNA Nanostructures for MolecularRobotics

• Project/Area Number: 23800006
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Bioinformatics/Life informatics
• Research Institution: Tohoku University
• Principal Investigator: HAMADA Shogo 東北大学, 大学院・工学研究科, 助教 (90610204)
• Project Period (FY): 2011 – 2012
• Project Status: Completed (Fiscal Year 2012)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 分子ロボティクス / DNAナノテクノロジー / DNAナノ構造 / DNAナノエンジニアリング / 自己集合 / 基板上成長 / T-motif

Research Abstract

Several types of flexible DNA nanostructures were designed and fabricated. The structures were designed to be compatible with state transition using strand displacement techniques. DNA nanostructures that represents the ideal formation of each state were observed, in order to evaluate the effectiveness of this design methodology.

Research Products

• [Journal Article] Theoretical Model of Substrate-Assisted Self-Assembly of DNA Nanostructures (2012)
  • Author(s): S. Hamada
  • Journal Title: RSC Advances Volume: 2 Issue: 19 Pages: 7406-7412
  • DOI: 10.1039/c2ra20764h
  • Peer Reviewed
• [Journal Article] Size-Controllable DNA Rings with Copper-Ion Modification (2012)
  • Author(s): J. Lee
  • Journal Title: Small Volume: 8(3) Issue: 3 Pages: 374-377
  • DOI: 10.1002/smll.201101561
  • Peer Reviewed
• [Presentation] Substrate-AssistedSelf-Assembly of DNA Nanostructures (2012)
  • Author(s): Hamada, S.
  • Organizer: 1st DNA Nanotechnology Forum
  • Place of Presentation: Daejeon, Korea
  • Year and Date: 2012-12-17
• [Presentation] A Preliminary Study on Colloidal Crystallization of DNA Motifs (2012)
  • Author(s): Hamada, S., Murata, S.
  • Organizer: 9th Annual Conference Foundations of Nanoscience (FNANO12)
  • Place of Presentation: Snowbird, UT. USA
  • Year and Date: 2012-04-17
• [Presentation] A Preliminary Study on Colloidal Crystallization of DNA Motifs (2012)
  • Author(s): Shogo Hamada
  • Organizer: Foundations of Nanoscience 2012
  • Place of Presentation: Snowbird, UT (米国)
  • Invited
• [Presentation] Theoretical Model of Substrate-Assisted Self-Assembly of DNA Motif (2011)
  • Author(s): Hamada, S., Murata, S.
  • Organizer: 17th International Conference on DNA Computing and Molecular Programming
  • Place of Presentation: Pasadena, CA.USA
  • Year and Date: 2011-09-22
• [Presentation] Theoretical Model of Substrate-Assisted Self-Assembly of DNA Motif (2011)
  • Author(s): Shogo Hamada
  • Organizer: 17th International Conference on DNA Computing and Molecular Programming
  • Place of Presentation: California Institute of Technology, Pasadena, CA.USA
  • Year and Date: 2011-09-22
• [Presentation] Theory of Substrate-Assisted Self-Assembly of DNA Nanostructures (2011)
  • Author(s): Hamada, S., Murata, S.
  • Organizer: Foundations of Nanoscience 2011
  • Place of Presentation: Snowbird,UT.USA
  • Year and Date: 2011-04-12
• [Presentation] Theory of Substrate-Assisted Self-Assembly of DNA Nanostructures (2011)
  • Author(s): Shogo Hamada
  • Organizer: Foundations of Nanoscience 2011
  • Place of Presentation: Snowbird, UT.USA
  • Year and Date: 2011-04-12
• [Book] DNAナノエンジニアリング (2011)
  • Author(s): 小宮健,瀧ノ上正浩,田中文昭,浜田省吾,村田智
  • Publisher: 近代科学社