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Development of micro circulation camera device for analysis of total artificial heart driving pattern

Research Project

Project/Area Number 23800020
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionThe University of Tokyo

Principal Investigator

INOUE Yusuke  東京大学, 大学院・工学系研究科, 特任研究員 (80611079)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords微小循環 / 血管新生 / 人工心臓 / 拍動流 / 顕微鏡 / 完全人工心臓 / 体内埋込型カメラ / 超小型顕微鏡 / 足場材料 / 拍動流・連続流 / 循環生理学 / カメラ / TAH
Research Abstract

We developed implantable microscope for micro circulation. We developed 3 type diameter device. The observation microscope has scaffold for angiogenesis. And we get stable data with this device. We experiment 6 times use with Total Artificial Heart. The animal with artificial heart living 121days maximum, and we observed our observation device. We change the heart drive pattern, exercise stress test, dose a medicine. We analyze the data. We found the difference of flow in the micro circulation via pattern of artificial heart moving.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • Research Products

    (45 results)

All 2013 2012 2011 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (38 results) Remarks (4 results)

  • [Journal Article] The helical flow pump with a hydrodynamic levitation impeller2012

    • Author(s)
      Abe Y, Ishii K, Isoyama T, Saito I, Inoue Y, Ono T, Nakagawa H, Nakano E, Fukazawa K, Ishihara K, Fukunaga K, Ono M, Imachi K
    • Journal Title

      J Artif Organs

      Volume: 15 Issue: 4 Pages: 331-340

    • DOI

      10.1007/s10047-012-0659-z

    • NAID

      10031145870

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of Normal-Suction Boundary Control Method Based on Inflow Cannula Pressure Waveform for the Undulation Pump Ventricular Assist Device2012

    • Author(s)
      Kohei Ishii, Itsuro Saito, Takashi Isoyama, Hidemoto Nakagawa, Nakano Emiko, Toshiya Ono, Wei Shi, Yusuke Inoue, and Yusuke Abe
    • Journal Title

      Artificial Organs

      Volume: 36(9) Issue: 9 Pages: 812-816

    • DOI

      10.1111/j.1525-1594.2012.01451.x

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of an implantable small camera for angiogenesis2011

    • Author(s)
      Yusuke Inoue, et al
    • Journal Title

      ASAIO Journal

      Volume: 57-2 Issue: 2 Pages: 123-123

    • DOI

      10.1097/01.mat.0000395437.21150.99

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 螺旋流血液ポンプの原理の検討2013

    • Author(s)
      石井耕平、細田享平、磯山隆、斎藤逸郎、有吉洸希、井上雄介、佐藤雅巳、原伸太郎、李欣陽、呉昇原、小野俊哉、中川英元、井街宏、阿部裕輔
    • Organizer
      第41回人工心臓と補助循環懇話会学術集会
    • Place of Presentation
      信州湯田中温泉よろづや
    • Year and Date
      2013-02-02
    • Related Report
      2012 Final Research Report
  • [Presentation] 完全人工心臓用螺旋流血液ポンプの内部流れ解析2013

    • Author(s)
      石井耕平、西田正浩、細田享平、磯山隆、有吉洸希、斎藤逸郎、中川英元、小野俊哉、井上雄介、井街宏、阿部裕輔
    • Organizer
      日本機械学会第25回バイオエンジニアリング講演会
    • Place of Presentation
      産業技術総合研究所つくばセンター
    • Related Report
      2012 Final Research Report
  • [Presentation] 螺旋流血液ポンプの溶血特性向上に向けた検討2012

    • Author(s)
      石井耕平、細田享平、磯山隆、有吉洸希、斎藤逸郎、井上雄介、佐藤雅巳、原伸太郎、小野俊哉、中川英元、井街宏、阿部裕輔
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2012-11-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 螺旋流型補助人工心臓用ハイブリッド脱血カニューレの研究2012

    • Author(s)
      井上雄介,中野英美子,磯山隆,斎藤逸郎,小野俊哉,石井耕平,佐藤雅巳,原信太郎,呉昇原,李欣陽,有吉洸希,細田享平,川瀬由希乃,中川基貴,中川英元,関野正樹,井街宏,阿部裕輔
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2012-11-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 完全人工心臓用螺旋流血液ポンプの基礎特性解析2012

    • Author(s)
      石井耕平、細田享平、西田正浩、磯山隆、有吉洸希、斎藤逸郎、中川英元、小野俊哉、井上雄介、井街宏、阿部裕輔
    • Organizer
      定常流ポンプ研究会2012
    • Place of Presentation
      福岡(アクロス福岡)
    • Year and Date
      2012-11-22
    • Related Report
      2012 Final Research Report
  • [Presentation] The helical flow pump and the helical flow total artificial heart2012

    • Author(s)
      Yusuke Abe, Kohei Ishii, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Toshiya Ono, Hidemoto Nakagawa, Kou Imachi
    • Organizer
      39th Congress of ESAO
    • Place of Presentation
      Academy of Music and Theatre, Rostock, Germany
    • Year and Date
      2012-09-29
    • Related Report
      2012 Final Research Report
  • [Presentation] DEVELOPMENT OF HYBRID INFLOW CANNULA FOR VENTRICULAR ASSIST DEVICES2012

    • Author(s)
      Yusuke Inoue, Emiko Nakano, Itsuro Saito, Takashi Isoyama, Hidemoto Nakagawa, Toshiya Ono, Kohei Ishii, Koki Ariyoshi, Kou Imachi, Yusuke Abe
    • Organizer
      39th Congress of ESAO
    • Place of Presentation
      Academy of Music and Theatre, Rostock, Germany
    • Year and Date
      2012-09-28
    • Related Report
      2012 Final Research Report
  • [Presentation] The helical flow total artificial heart: initial results of animal experiment2012

    • Author(s)
      Yusuke Abe, Kohei Ishii, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Hidemoto Nakagawa, Toshiya Ono, Kazuhiko Ishihara, Minoru Ono, Kou Imachi
    • Organizer
      ISRBP2012 (20th Congress of the International Society for Rotary Blood Pumps)
    • Place of Presentation
      Grand Cevahir Hotel, Istanbul, Turkey
    • Year and Date
      2012-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of Hybrid Inflow Cannula for Helical Flow Ventricular Assist Device2012

    • Author(s)
      Yusuke Inoue, Emiko Nakano, Itsuro Saito, Takashi Isoyama, Hidemoto Nakagawa, Toshiya Ono, Kohei Ishii, Koki Ariyoshi,Kou Imachi, Yusuke Abe
    • Organizer
      ISRBP2012 (20th Congress of the International Society for Rotary Blood Pumps)
    • Place of Presentation
      Grand Cevahir Hotel, Istanbul, Turkey
    • Year and Date
      2012-09-21
    • Related Report
      2012 Final Research Report
  • [Presentation] CFD解析に基づいた人工心臓血液ポンプの設計2012

    • Author(s)
      細田恭平
    • Organizer
      第14回生体物理医学専攻セミナー
    • Place of Presentation
      東京(東京大学医学部付属病院)
    • Year and Date
      2012-06-20
    • Related Report
      2012 Final Research Report
  • [Presentation] The helical flow total artificial heart: design concept and initial development2012

    • Author(s)
      Yusuke Abe, Kohei Ishii, Takashi Isoyama, Itsuro Saito, Yusuke Inoue, Toshiya Ono, Hidemoto Nakagawa, Kazuhiko Ishihara, Minoru Ono, Kou Imachi
    • Organizer
      ASAIO 58th annual conference
    • Place of Presentation
      Fairmont San Franciscol, San Francisco, California, USA
    • Year and Date
      2012-06-15
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of an Implantable Small Observation Camera with Scaffold Chamber for Angiogenesis2012

    • Author(s)
      Yusuke Inoue, Itsuro Saito, Takashi Isoyama, Hidemoto Nakagawa, Toshiya Ono, Kohei Ishii, Koki Ariyoshi, Emiko Nakano, Kou Imachi, Yusuke Abe
    • Organizer
      World Congress 2012 Medical Physics and Biomedical Engineering
    • Place of Presentation
      Beijing International Convention Center, Beijing, China
    • Year and Date
      2012-05-27
    • Related Report
      2012 Final Research Report
  • [Presentation] 螺旋流完全人工心臓の開発2012

    • Author(s)
      阿部裕輔、石井耕平、磯山隆、斉藤逸郎、井上雄介、小野俊哉、中川英元、中野英美子、深沢今日子、石原一彦、福長一義、小野稔、井街宏
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2012-05-11
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] ハイブリッド型人工材料を用いた補助人工心臓用脱血カニューレの開発2012

    • Author(s)
      井上雄介,中野英美子,磯山隆,斎藤逸郎,中川英元,小野俊哉,石井耕平,有吉洸希,細田享平,井街宏,阿部裕輔
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2012-05-11
    • Related Report
      2012 Final Research Report
  • [Presentation] 螺旋流完全人工心臓のための動圧軸受の開発2012

    • Author(s)
      石井耕平、細田享平、磯山隆、有吉洸希、斎藤逸郎、大橋広宜、中川英元、小野俊哉、井上雄介、中野英美子、井街宏、阿部裕輔
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2012-05-10
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 螺旋流人工心臓システムの研究と開発2012

    • Author(s)
      井上雄介
    • Organizer
      医用アクチュエーション研究会(招待講演)
    • Place of Presentation
      東北大学、(宮城県仙台市)
    • Year and Date
      2012-03-30
    • Related Report
      2012 Final Research Report
  • [Presentation] 螺旋流人工心臓システムの研究と開発2012

    • Author(s)
      井上雄介
    • Organizer
      医用アクチュエーション研究会
    • Place of Presentation
      東北大学(宮城県仙台市)(招待講演)
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 生体内血管新生における細胞播種による影響の観察2012

    • Author(s)
      井上雄介
    • Organizer
      第24回代用臓器再生医学研究会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2012-01-28
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 完全人工心臓における微小樹幹血行動態の実時間観察2011

    • Author(s)
      井上雄介
    • Organizer
      第49回日本人工臓器学会
    • Place of Presentation
      都市センターホテル(東京都千代田区)
    • Year and Date
      2011-11-27
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] GRANT成果報告:完全人工心臓における微小循環動態の実時間観察2011

    • Author(s)
      井上雄介
    • Organizer
      第49回日本人工臓器学会
    • Place of Presentation
      日本都市センターホテル(東京都千代田区)
    • Year and Date
      2011-11-26
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] Development of an implantable small camera for angiogenesis2011

    • Author(s)
      Yusuke Inoue
    • Organizer
      XXXVIII Congress of the European Society for Artificial Ogans
    • Place of Presentation
      ポ ルトコングレスセンター(ポルトガル)
    • Year and Date
      2011-09-11
    • Related Report
      2012 Final Research Report
  • [Presentation] Development of an implantable small camera for angiogenesis2011

    • Author(s)
      Yusuke Inoue
    • Organizer
      XXXVIII Congress of the European Society for Artificial Ogans
    • Place of Presentation
      ポルトコングレスセンター(ポルトガル)
    • Year and Date
      2011-09-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] ハイブリッド型人工材料を用いた補助人工心臓用脱血カニューレの開発

    • Author(s)
      井上雄介
    • Organizer
      第51回日本生体医工学会大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of an Implantable Small Observation Camera with Scaffold Chamber for Angiogenesis

    • Author(s)
      Yusuke Inoue
    • Organizer
      World Congress 2012 Medical Physics and Biomedical Engineering
    • Place of Presentation
      Beijing International Convention Center, Beijing, China
    • Related Report
      2012 Annual Research Report
  • [Presentation] Hyderodynamic bearing for the helical flow total artificial heart

    • Author(s)
      Kohei Ishii
    • Organizer
      ASAIO 58th annual conference
    • Place of Presentation
      Fairmont San Franciscol, San Francisco, California, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] The helical flow total artificial heart: design concept and initial development

    • Author(s)
      Yusuke Abe
    • Organizer
      ASAIO 58th annual conference
    • Place of Presentation
      Fairmont San Franciscol, San Francisco, California, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Development of Hybrid Inflow Cannula for Helical Flow Ventricular Assist Device

    • Author(s)
      Yusuke Inoue
    • Organizer
      ISRBP2012 (20th Congress of the International Society for Rotary Blood Pumps)
    • Place of Presentation
      Grand Cevahir Hotel, Istanbul, Turkey
    • Related Report
      2012 Annual Research Report
  • [Presentation] The helical flow total artificial heart: initial results of animal experiment

    • Author(s)
      Yusuke Abe
    • Organizer
      ISRBP2012 (20th Congress of the International Society for Rotary Blood Pumps)
    • Place of Presentation
      Grand Cevahir Hotel, Istanbul, Turkey
    • Related Report
      2012 Annual Research Report
  • [Presentation] DEVELOPMENT OF HYBRID INFLOW CANNULA FOR VENTRICULAR ASSIST DEVICES

    • Author(s)
      Yusuke Inoue
    • Organizer
      39th Congress of ESAO
    • Place of Presentation
      Academy of Music and Theatre, Rostock, Germany
    • Related Report
      2012 Annual Research Report
  • [Presentation] The helical flow pump and the helical flow total artificial heart

    • Author(s)
      Yusuke Abe
    • Organizer
      39th Congress of ESAO
    • Place of Presentation
      Academy of Music and Theatre, Rostock, Germany
    • Related Report
      2012 Annual Research Report
  • [Presentation] CFD解析を用いたEmergency Life Support System用血液ポンプ最適設計についての検討

    • Author(s)
      有吉洸希
    • Organizer
      日本生体医工学会 関東支部 若手研究者発表会2011
    • Place of Presentation
      東京(東京都市大学)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 完全人工心臓用螺旋流血液ポンプの基礎特性解析

    • Author(s)
      石井耕平
    • Organizer
      日本定常流ポンプ研究会2012
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] CFD解析によるEmergency Life Support System(ELSS)用血液ポンプ設計

    • Author(s)
      有吉洸希
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 螺旋流型補助人工心臓用ハイブリッド脱血カニューレの研究

    • Author(s)
      井上雄介
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 螺旋流完全人工心臓におけるテーブル型流量差圧推定モデルの構築

    • Author(s)
      原伸太郎
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 螺旋流血液ポンプにおける流路形状と内部流れの関係に関する研究

    • Author(s)
      細田享平
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 螺旋流血液ポンプの溶血特性向上に向けた検討

    • Author(s)
      石井耕平
    • Organizer
      第50回日本人工臓器学会大会
    • Place of Presentation
      福岡(アクロス福岡)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 螺旋流血液ポンプの原理の検討

    • Author(s)
      石井耕平
    • Organizer
      第41回人工心臓と補助循環懇話会学術集会
    • Place of Presentation
      信州湯田中温泉よろづや
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.gr.jp/

    • Related Report
      2012 Final Research Report
  • [Remarks] 東京大学関野研究室

    • URL

      http://www.bee.t.u-tokyo.ac.jp/index_j.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] 東京大学医用生体工学講座

    • URL

      http://www.bme.gr.jp

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.gr.jp

    • Related Report
      2011 Annual Research Report

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Published: 2011-09-05   Modified: 2019-07-29  

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