Revelation of linkage between the change of cortical neural activity and the induction mechanism of plasticity during motor learning with the newest optical methods
Project/Area Number |
23800071
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Neuroscience in general
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Research Institution | National Institute for Basic Biology |
Principal Investigator |
MASAMIZU Yoshito 基礎生物学研究所, 光脳回路研究部門, 特別協力研究員 (90608530)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | カルシウムイメージング / 光子励起顕微鏡 / 運動学習 / 2光子励起顕微鏡 / 2光子カルシウムイメージング / 光遺伝学 |
Research Abstract |
I performed two-photon calcium imaging in L2/3 and L5 of the mouse primary motor cortex during a few weeks of a self-initiated lever-pull task, identifying L2/3 and L5 based on the cortical depth of the imaging plane. During motor learning, increasing firing rate of neurons was frequently observed in L5 than L2/3
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Report
(3 results)
Research Products
(3 results)