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Developmnt of early detection of leukemia cells by employing soft computing an dielectrophoresis

Research Project

Project/Area Number 23800072
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Sensitivity informatics/Soft computing
Research InstitutionFuzzy Logic Systems Institute

Principal Investigator

EGUCHI Masanori  一般財団法人ファジィシステム研究所, 研究部, 研究員 (60613594)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords誘電泳動 / 進行波電界 / 血液細胞 / 白血病 / 誘電泳動現象 / ソフトコンピューティング / 白血病細胞 / 超早期診断
Research Abstract

The Bottle neck Fork-Trace (BF) electrode which can transport and separate all blood cells in chamber have been developed for early detection of leukemia.The BF electrode is possible to transport all particles from the entire chamber to the electrode gap by Traveling-wave electric fields at first, and then separate them by dielectrophoresis. Leukocytes in medium were separated from erythrocytes by using the electrode. The dielctrophoretic characteristics of leukemia cells (HL-60, BALL-1) were measured, and the leukemia cells were separated form normal leukocytes by difference in dielectric property.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • Research Products

    (16 results)

All 2013 2012 2011 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (9 results) Remarks (3 results)

  • [Journal Article] Particle Separation by Employing Non-uniform Electric Fields, Traveling-wave Electric Fields and Inclined Gravity2012

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, and Takeshi Yamakawa
    • Journal Title

      Intelligent Automation and Soft Computing

      Volume: Vol.18, No.2 Issue: 2 Pages: 121-137

    • DOI

      10.1080/10798587.2008.10643231

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Separation of Leukemia Cells from Blood by Employing Dielectrophoresis2012

    • Author(s)
      Hiroko Imasato, Takeshi Yamakawa, and Masanori Eguchi
    • Journal Title

      Intelligent Automation and Soft Computing

      Volume: Vol.18, No.2 Issue: 2 Pages: 139-152

    • DOI

      10.1080/10798587.2008.10643232

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Particle Separation by Employing Non-Uniform Electric Fields, Traveling-Wave Electric Fields and Inclined Gravity2012

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, Takeshi Yamakawa
    • Journal Title

      Intelligent Automation and Soft Computing

      Volume: 18 Pages: 121-137

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Separation of Leukemia Cells from Blood by Employing Dielectrophoresis2012

    • Author(s)
      Hiroko Imasato, Takeshi Yamakawa, Masanori Eguchi
    • Journal Title

      Intelligent Automation and Soft Computing

      Volume: 18 Pages: 139-152

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 誘電泳動と進行波電界を用いた血液細胞の分離2013

    • Author(s)
      江口 正徳,山川 烈
    • Organizer
      電子情報通信学会マイクロ波研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-06-28
    • Related Report
      2012 Final Research Report
  • [Presentation] 誘電泳動を用いた細胞分離用電極の高周波特性の計算2012

    • Author(s)
      黒木 太司,明石 歩,江口 正徳,山川 烈
    • Organizer
      電子情報通信学会マイクロ波研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-06-28
    • Related Report
      2012 Final Research Report
  • [Presentation] Separation of Blood Cells by Employing Dielectrophoresis and Traveling-wave Electric Fields2012

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, and Takeshi Yamakawa
    • Organizer
      Proc. Of World Automation Congress, in CD-ROM
    • Place of Presentation
      Puerto Vallarta(メキシコ)
    • Year and Date
      2012-06-25
    • Related Report
      2012 Final Research Report
  • [Presentation] Separation of Blood Cells by Employing Dielectrophoresis and Traveling-wave Electric Fields2012

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, Takeshi Yamakawa
    • Organizer
      World Automation Congress 2012
    • Place of Presentation
      Puerto Vallarta(メキシコ)(発表確定)
    • Year and Date
      2012-06-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Separation of Particles by Combining Dielectrophoresis and Traveling-wave Electroosmosis under Inclined Gravity2011

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, and Takeshi Yamakawa
    • Organizer
      Proceedings of the 24th Annual Conference of Biomedical Fuzzy Systems Association
    • Place of Presentation
      山口(招待講演)
    • Year and Date
      2011-10-30
    • Related Report
      2012 Final Research Report
  • [Presentation] Separation of Particles by Combining Dielectrophoresis and Traveling-wave Electroosmosis under Inclined Gravity2011

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, Takeshi Yamakawa
    • Organizer
      24th Annual Conference of Biomedical Fuzzy Systems Association
    • Place of Presentation
      山口大学(山口県)(招待講演)
    • Year and Date
      2011-10-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Separation of Blood Cells by Employing Dielectrophoresis and Traveling-wave Electric Fields

    • Author(s)
      Masanori Eguchi, Hiroko Imasato, Takeshi Yamakawa
    • Organizer
      World Automation Congress 2012
    • Place of Presentation
      Puerto Vallarta(メキシコ)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 誘電泳動と進行波電界を用いた血液細胞の分離

    • Author(s)
      江口 正徳,山川 烈
    • Organizer
      電子情報通信学会 マイクロ波研究会
    • Place of Presentation
      名古屋工業大学(名古屋)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 誘電泳動を用いた細胞分離用電極の高周波特性の計算

    • Author(s)
      黒木 太司,明石 歩,江口 正徳,山川 烈
    • Organizer
      電子情報通信学会 マイクロ波研究会
    • Place of Presentation
      名古屋工業大学(名古屋)
    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://flsi.cird.or.jp/personal_page/eguchi/index.html

    • Related Report
      2012 Final Research Report
  • [Remarks] 一般財団法人ファジィシステム研究所

    • URL

      http://flsi.cird.or.jp/DEP.html

    • Related Report
      2012 Annual Research Report
  • [Remarks] 一般財団法人ファジィシステム研究所 江口正徳

    • URL

      http://flsi.cird.or.jp/personal_page/eguchi/index.html

    • Related Report
      2012 Annual Research Report

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Published: 2011-09-05   Modified: 2019-07-29  

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