Study of the neural mechanisms involved in the disability of future prediction in depression
| Project/Area Number |
23830088
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Clinical psychology
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| Research Institution | Waseda University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | うつ病 / 集団認知行動療法 / 遅延割引 / fMRI / 将来予測 |
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| Research Abstract |
The purpose of this study was to reveal the neural mechanisms involved in the disability of future prediction in depression and the effects of cognitive behavioral therapy. Using the functional magnetic resonance imaging and delay discounting task, we compared depressed patients with healthy controls in the brain activity during delay discounting task. And, patients' brain activity during delay discounting task was compared before cognitive behavioral therapy and after that. As a result, we confirmed that depressed patients show the high delely discounting of loss comparting to healthy controls. We revealed that depressed patients' high delay discounting and neural activity related delay discounting was weakened by the cognitive behavioral therapy.
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Report
(3 results)
Research Products
(40 results)
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[Journal Article] Neural and Personality Correlates of Individual Differences Related to the Effects of Acute Tryptophan Depletion on Future Reward Evaluation.2012
Author(s)
Demoto Y, Okada G, Okamoto Y, Kunisato Y, Aoyama S, Onoda K, Munakata A, Nomura M, Tanaka SC, Schweighofer N, Doya K, Yamawaki S.
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Journal Title
Neuropsychobiology
Volume: 65 (2)
Issue: 2
Pages: 55-64
DOI
Related Report
Peer Reviewed
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[Presentation] The Association between Brain's Default Mode Network and Anhedonia: a Resting State FMRI Study2012
Author(s)
Kunisato, Y., Okamoto, Y., Okada, G., Nishiyama, Y., Kanai, Y., Sasaki- Aoki, S., Yoshimura, S., Katsuragawa, T., Suzuki, S., & Yamawaki, S.
Organizer
The 12th International Congress of Behavioral Medicine (ICBM)
Place of Presentation
Budapest, Hungary.
Year and Date
2012-08-29
Related Report
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[Presentation] DELAY DISCOUNTING CORRELATED WITH ACC AND PFC : A VBM STUDY2012
Author(s)
Kunisato,Y., Okamoto, Y., Okada, G., Nishiyama, Y., Kanai, Y., Sasaki-Aoki, S., Iwanaga, M., Yamawaki, S.
Organizer
The 16th Congress of International Society for Biomedical Research on Alcoholism (ISBRA)
Place of Presentation
Sapporo, Japan.
Related Report
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[Presentation] IMPAIRMENTS OF ATTENTIONAL FUNCTION RELATES TO DEPRESSIVE SYMPTOM DURING ABSTINENCE IN PATIENTS WITH ALCOHOL DEPENDENCE2012
Author(s)
Takebayashi, Y., Tanaka, K., Tukue, R., Okamoto, Y., Kunisato, Y., Okada, G., Tsukue, I., Shimohara, C., Konuma, K., Sugiura, Y., Yamawaki, S.
Organizer
The 16th Congress of International Society for Biomedical Research on Alcoholism (ISBRA)
Place of Presentation
Sapporo, Japan.
Related Report
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[Presentation] RELATIONSHIP BETWEEN ATTENTION CONTROL AND EMOTION DYSREGULATION IN ALCOHOL DEPENDENT PATIENTS2012
Author(s)
Tanaka, K., Takebayashi, Y., Tukue, R., Okamoto, Y., Kunisato, Y., Okada, G., Tsukue, I., Shimohara, C., Konuma, K., Sugiura, Y., Yamawaki, S.
Organizer
The 16th Congress of International Society for Biomedical Research on Alcoholism (ISBRA)
Place of Presentation
Sapporo, Japan.
Related Report
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[Presentation] RELATIONSHIP BETWEEN DELAY DISCOUNTING, ATTENTION CONTROL AND EMOTIONAL REGULATION IN ALCOHOLISM2012
Author(s)
Tsukue, R., Okamoto, Y., Kunisato, Y., Takebayashi, Y., Tanaka, K., Tsukue, I., Shimohara, C., Konuma, K., Okada, G., Sugiura, Y., Yamawaki, S.
Organizer
The 16th Congress of International Society for Biomedical Research on Alcoholism (ISBRA)
Place of Presentation
Sapporo, Japan.
Related Report
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[Presentation] Hippocampal Activation predicts Treatment Response to Antidepressant for Depression2011
Author(s)
Toki, S., Okamoto, Y., Onoda, K., Yoshimura, S., Kunisato, Y., Okada, G., Yamawaki, S.
Organizer
The 50 th annual meeting of American College of Neuropsychopharmacology (ACNP)
Place of Presentation
Hawaii, USA.
Year and Date
2011-12-07
Related Report
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[Presentation] The volume of right superior temporal gyrus predicts treatment response in treatment-resistant depression patients after cognitive behavioral group therapy.2011
Author(s)
Kunisato, Y., Okamoto, Y., Yoshimura, S., Ueda, K., Matsunaga, M., Okada, G., Onoda, K., Suzuki, S., & Yamawaki, S.
Organizer
the 3rd Asian Cognitive Behavior Therapy Conference
Place of Presentation
Seoul, Korea.
Year and Date
2011-07-15
Related Report
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[Presentation] The relationship between frontal and temporal activation and automatic thoughts: Multi-channel near-infared spectroscopy (NIRS) study.2011
Author(s)
Yokoyama,S., Noda, T., Koseki, S., Ito, D., Kunisato, Y., Suyama, H., Sugimura, Y., Ishihara, N., Shimizu, Y., Nakazawa, K., & Suzuki, S.
Organizer
the 3rd Asian Cognitive Behavior Therapy Conference
Place of Presentation
Seoul, Korea.
Year and Date
2011-07-14
Related Report
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