Elucidation of molecular mechanism for maintaining chromosome alignment regulated by novel protein, CAMP
| Project/Area Number |
23870001
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Cell biology
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| Research Institution | Tohoku University |
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Principal Investigator |
ITOH Go 東北大学, 加齢医学研究所, 助教 (60607563)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 細胞・組織 / 生物・生体工学 / プロテオーム / 分子機械 / バイオテクノロジー |
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| Research Abstract |
Accurate chromosome segregation requires proper chromosome alignment at equatorial region in metaphase. Recently, we identified novel molecule, CAMP, which plays an important role in a maintaining of chromosome alignment (EMBO J, 2011). In this study, we examined a molecular mechanism for the maintaining of chromosome alignment mediated by CAMP. Therefore, I identified a CAMP interacting protein during mitosis and then assessed a relationship between CAMP and the interacting protein involved in maintainingof chromosome alignment.
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Report
(3 results)
Research Products
(9 results)
