First step toward ascertaining bacteriocin productionfrom lactic acid bacteria in animal intestinal tract
Project/Area Number |
23880019
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Zootechnical science/Grassland science
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Research Institution | Okayama University |
Principal Investigator |
ARAKAWA Kensuke 岡山大学, 大学院・環境生命科学研究科, 助教 (50609930)
|
Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 乳酸菌 / バクテリオシン / 抗菌ペプチド / Lactobacillus gasseri |
Research Abstract |
Most strains of Lactobacillus gasseri, a predominant in human small intestinal tract, produce an antibacterial peptide, namely bacteriocin “gassericin T”. In this study, we demonstrated that gassericin T is produced from 9 genes in the chromosome of its producer, and that it consists of two simple peptides associated with each other in solution. These results would contribute to future research on the effect of bacteriocins on host-gut microbiota and health.
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Report
(3 results)
Research Products
(13 results)
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[Presentation] 二成分性バクテリオシン「ガセリシンT」のGxxxGモチーフが抗菌活性に及ぼす影響.
Author(s)
安田成美, 川井泰, 伊藤喜之, 荒川健佑, 中村圭志, 鈴木はるか, 郭暁艶, 水谷陽, 西村順子, 北澤春樹, 齋藤忠夫.
Organizer
日本乳酸菌学会2012年大会
Place of Presentation
つくば国際会議場(茨城県)
Related Report
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