Roles for nucleolus in the function of long noncoding RNA

• Project/Area Number: 23890025
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Biological pharmacy
• Research Institution: University of Tsukuba
• Principal Investigator: KISHIMOTO Hiroyuki 筑波大学, 生命環境系, 講師 (50344750)
• Project Period (FY): 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: lncRNA / 核小体 / X染色体不活性化

Research Abstract

Although relationships between lncRNA and nucleolus have been implicated, the molecular mechanism is not described yet. In this project the regulation of lncRNA localization will be explored by screening nucleolar proteins which is involved in the function of lncRNA.