| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
To evaluate the collateral circulation activated by cerebral arteriogenesis, we established the visualization of the leptomeningial l artery in the chronic cerebral hypoperfusion mouse mode using the Latex-carbon ink fixation methods. We investigated the aretriogenesis with PCNA staining, and successfully found the promoting the collateral circulation resulted from arteriogenesis in acute stage of cerebral ischemia.We also established the non-invasive MRI methods to evaluate the collateral circulation in acute stroke patients and reported these collateral sign have an important prognostic value in acute ischemic stroke of proximal arterial occulusion.
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