The effect of common anesthetic agents to the developing mouse brain
| Project/Area Number |
23890054
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SATOMOTO Maiko 東京医科歯科大学, 医学部附属病院, 助教 (10611551)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 幼若脳 / 麻酔薬 / アポトーシス / 学習障害 |
|---|
| Research Abstract |
Early exposure to general anesthesia causes widespread apoptotic neurodegeneration in the developing rodents and rhesus monkeys brain.In this study, we observed that preinjection of nicotine markedly reduced neuronal apoptosis caused by sevoflurane exposure in the developing brain.
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Report
(3 results)
Research Products
(5 results)
