Increased occlusal vertical dimension induces modulation of masticatory feedforward control
Project/Area Number |
23890056
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Orthodontic/Pediatric dentistry
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
SHIBATA Mai 東京医科歯科大学, 医歯学総合研究科, 医員 (00613689)
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Research Collaborator |
KATO Chiho 東京医科歯科大学, 医歯学総合研究科, 大学院生
FUNAKI Yukiha 東京医科歯科大学, 医歯学総合研究科, 大学院生
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Project Period (FY) |
2011 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
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Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | 運動学習 / 咬合高径増加 / 一次運動野 / feedback / 開口反射 / 咬合高径挙上 / 皮質咀嚼野 / 大脳皮質一次運動野 / 筋電図 / ラット / 電気生理学 |
Research Abstract |
Previous studies have demonstrated that functional plasticity in the primary motor cortex (M1) is related to motor-skill learning and changes in the environment. Increased occlusal vertical dimension (iOVD) may modulate mastication, such as in the masticatory cycle, cycle, and the firing properties of jaw-muscle spindles. However, little is known about the changes in motor representation within the face primary motor cortex(face-M1) after iOVD. The purpose of the present study was to determine the effect of iOVD on the face-M1 using intracortical microstimulation (ICMS). In an iOVD group, the maxillary molars were built-up by 2 mm with acrylic. The electromyographic (EMG) activities from the left (LAD) and right (RAD) anterior digastric (AD), masseter and genioglossus (GG) muscles elicited by ICMS within the right face-M1 were recorded 1, 2 and 8 weeks after iOVD. IOVD was associated with a significant increase in the number of sites within the face-M1 from which ICMS evoked LAD and/or GG EMG activities, as well as a lateral shift in the center of gravity of the RAD and LAD muscles at 1 and 2 weeks, but not at 8 weeks. These findingssuggest that a time-dependent neuroplastic change within the rat face-M1 occurs in association with iOVD. This may be related to the animal’s ability to adapt to a change in the oral environment.
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Report
(3 results)
Research Products
(7 results)