Molecular biological factors in drug-induced gingival overgrowth
| Project/Area Number |
23890063
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
SHIMIZU Taro 新潟大学, 医歯学総合病院, 医員 (60609121)
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| Project Period (FY) |
2011 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 歯肉増殖症 / 歯肉溝浸出液 / マルチプレックスサスペンションアレイ / マルチプレックスサスペンションシステム / タンパク質 |
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| Research Abstract |
Gingival clevicular fluid (GCF) was extracted from gingival overgrowth sites and analyzed using a Multiplex suspension array system. A number of specifically expressed cellular growth factors, cell attachment factors, and inflammatory cytokines were examined from GO sites. The results showed significantly up-regulated levels of IL-8, as well as elevated levels of IL-1 beta,TGF-beta, and VEGF-A. Those results were reported at the American Academy of Periodontology.
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Report
(3 results)
Research Products
(3 results)
