| Project/Area Number |
23890065
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Biological pharmacy
|
|---|
| Research Institution | University of Toyama |
|---|
Principal Investigator |
ISHIKAWA Mitsuru 富山大学, 大学院・医学薬学研究部(薬学), 助教 (10613995)
|
|---|
| Project Period (FY) |
2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | アクチン / SRF / 転写因子 / 樹状突起 / Rho |
|---|
| Research Abstract |
In characterizing MKL1 transcripts expressed in rat brain, we have identified a novel transcript in addition to the other two transcripts. Functional comparison of these isoforms with regard to their ability to localize to the nucleus, drive SRE-mediated transcription and dendritic morphology revealed that one of the MKL1 isoforms is more active than the others in all these assays.
|
