| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
In vivo and in vitro analyses were performed to study transport mechanisms for cationic drugs, such as [^3H]verapamil, at the blood-retinal barrier （BRB).The results obtained suggested the involvement of carrier-mediated transport system in the influx transport of cationic drugs across the inner BRB. Furthermore, orphan transporters were identified as candidate molecules responsible for drug transport at the inner BRB.
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