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The role of heparan sulfate in osteoporosis.

Research Project

Project/Area Number 23890074
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionGifu University

Principal Investigator

TAKIGAMI Iori  岐阜大学, 医学部附属病院, 医員 (90610410)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords骨粗鬆症 / ヘパラン硫酸 / 遺伝性多発性外骨腫症 / ゲノム DNA / ゲノム
Research Abstract

The screening for osteoporosis of hereditary multiple exostosis patients indiated osteopenia compare with healthy adults. The analysis of genomic DNA revealed that osteopenia occurs regardless of its type of gene mutation.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • Research Products

    (2 results)

All 2013

All Presentation (2 results)

  • [Presentation] Targeted Disruption of Heparan Sulfate in Osteoblasts Leads to a Severe Osterporotic Phenotype inMice2013

    • Author(s)
      Satoshi Nozawa, Fumitoshi Irie, Kazu Matsumoto, Iori Takigami, Yu Yamaguchi
    • Organizer
      Orthopaedic Research Society 2013
    • Place of Presentation
      San Antonio, Texas, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Targeted Disruption of Heparan Sulfate in Osteoblasts Leads to a Severe Osterporotic Phenotype in Mice2013

    • Author(s)
      Satoshi Nozawa
    • Organizer
      Orthopaedic Research Society
    • Place of Presentation
      San Antonio, Texas, USA
    • Related Report
      2012 Annual Research Report

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Published: 2011-09-05   Modified: 2019-07-29  

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