The study of TGFβ associated novel biomarker that could detect high risk premalignant lesion.
Project/Area Number |
23890080
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
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Research Institution | Nagoya University |
Principal Investigator |
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Project Period (FY) |
2011 – 2012
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Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 口腔癌 / 前癌病変 / CD109 / 免疫組織化学 / 診断マーカー |
Research Abstract |
Immunohistochemical analysis using paraffin embedded samples of oral dyisplasia showed CD109 positive rate of high-risk group was significantly higher than that of control group. In immunohistochemical analysis of tongue squamous cell carcinoma (TSCC), a positive relation was existed between Ki-67 and CD109 expression in well or moderately differentiated TSCC including CIS.
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Report
(3 results)
Research Products
(7 results)
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[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma2013
Author(s)
Hagiwara S, Yamamoto N, Furue H, Sakakura H, Shigetomi T, Murakumo Y, Hibi H, Takahashi M, Ueda M
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Journal Title
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Volume: 25
Issue: 3
Pages: 276-287
DOI
Related Report
Peer Reviewed
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[Journal Article] Pathological analysis of Ki-67 and CD109 expression in tongue squamous cell carcinoma'2012
Author(s)
Sumitaka Hagiwara, Noriyuki Yamamoto, Hiroki Furue, Hiroki Sakakura, Toshio Shigetomi, Yoshiki Murakumo, Hideharu Hibi, Masahide Takahashi, Minoru Ueda.
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Journal Title
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
Volume: Accepted 3
URL
Related Report
Peer Reviewed
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