| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Research Abstract |
Experimental methods for analyzing the osteoclast function wasestablished. For in vitro experiment, osteoclast precursor was co-cultured with osteoblast to differentiate to osteoclast. For in vivo experiment, mechanical testing machine was made for tibia loading. Using this machine the increasing of bone mass was evaluated. To study membrane potential of osteoclast, membrane potential change was measured by imaging technique.
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