Characterization of immunoregulation by Th17 cell on Periodontal disease model
| Project/Area Number |
23890217
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nihon University |
|---|
Principal Investigator |
KOBAYASHI Ryoki 日本大学, 松戸歯学部, 助手(専任扱) (10609085)
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| Project Period (FY) |
2011 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | 感染症 / 免疫学 / 歯周疾患 / TH17 / 口腔粘膜 / Th17 |
|---|
| Research Abstract |
In order to clarify the mechanism of Periodontal diseases, we characterized the immunoregulatory effect by Th17 cells in the inflamed gingiva of mice with alveolar bone resorption. In this study, we employ Aggregatibacter actinomycetemcomitansone, one of the higher risk factors for induce of inflammation to gingiva and alveolar bone loss.
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Report
(3 results)
Research Products
(8 results)
