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Novel Cardiac Workload Evaluation System Based on Echocardiography and MRI Flow Visualization Method and its Application to the Cardiovascular Disease in Elderly Patients

Research Project

Project/Area Number 23890259
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionKitasato University

Principal Investigator

ITATANI Keiichi  北里大学, 医学部, 准教授 (70458777)

Project Period (FY) 2011 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords血流可視化 / 心負荷 / 大動脈弁閉鎖不全症 / 心臓超音波 / 心臓 MRI / 心機能評価 / 心機能 / 心臓MRI / 可視化血流 / 心臓弁膜症
Research Abstract

For the development of the cardiac workload evaluation system in elderly patients based on the echocardiography and cardiac MRI, we at first, developed blood flow visualization method using echocardiography and cardiac MRI. Echocardiography VFM (vector flow mapping) has been established and MRI blood flow visualization software has been also created using PC (phase contrast) MRI. From the visualized blood flow velocity vector field, we developed a system to calculate flow energy loss. Then we applied these systems to aortic valve regurgitation cases, and 3 cases were evaluated with echocardiography, and other 3 cases were evaluated with MRI. From the results, flow energy loss caused by the regurgitation jet was proven to be closely related to the flow collision with transmitral flow in the left ventricle.

Report

(3 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • Research Products

    (57 results)

All 2013 2012 2011

All Journal Article (25 results) (of which Peer Reviewed: 22 results) Presentation (24 results) (of which Invited: 9 results) Patent(Industrial Property Rights) (8 results) (of which Overseas: 3 results)

  • [Journal Article] Strategies for the creation and maintenance of reconstructed arteriovenous fistulas using the forearm basilic vein2013

    • Author(s)
      Kumano S, Itatani K, Shiota J, Gojo S, Izumi N, Kasahara H, Homma Y, Tagawa H
    • Journal Title

      Ther Apher Dial

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Surgical strategy for severe aortic hypoplasia and aortic stenosis with ventricular septal defect and normal left ventricle2013

    • Author(s)
      Tomoyasu T, Oka N, Miyamoto T, Kitamura T, Itatani K, Inoue N, Ishii M, Miyaji K
    • Journal Title

      Pediatr Cardiol

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intraventricular flow velocity vector visualization based on the continuity equation and measurements of vorticity and wall shear stress2013

    • Author(s)
      Itatani K, Okada T, Uejima T, Tanaka T, Ono M, Miyaji K, Takenaka K
    • Journal Title

      Jpn J Appl Physic

    • NAID

      210000142537

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Subacute presentation of right ventricular perforation after pacemaker implantation2013

    • Author(s)
      Koyama S, Itatani K, Kyo S, Aoyama R, Ishiyama T, Harada K, Ono M
    • Journal Title

      Ann Thracic Cardiovasc Surg

      Volume: 19(1) Pages: 73-5

    • NAID

      10031176198

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intraventricular flow velocity vector visualization based on the continuity equation and measurements of vorticity and wall shear stress2013

    • Author(s)
      Itatani K, Okada T, Uejima T, Tanaka T, Ono M, Miyaji K, Takenaka K.
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: in-press

    • NAID

      210000142537

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Strategies for the creation and maintenance of reconstructed arteriovenous fistulas using the forearm basilic vein2013

    • Author(s)
      Kumano S, Itatani K, Shiota J, Gojo S, Izumi N, Kasahara H, Homma Y, Tagawa H.
    • Journal Title

      Ther Apher Dial

      Volume: in-presss

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surgical strategy for severe aortic hypoplasia and aortic stenosis with ventricular septal defect and normal left ventricle.2013

    • Author(s)
      Tomoyasu T, Oka N, Miyamoto T, Kitamura T, Itatani K, Inoue N, Ishii M, Miyaji K
    • Journal Title

      Pediatr Cardiol.

      Volume: 34(5): Pages: 1107-11

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aortic Valve Replacement and Concomitant Coronary Artery Bypass Grafting in a Patient with Infective Endocarditis and Anomalous Origin of the Right Coronary Artery from the Opposite Sinus of Valsalva.2013

    • Author(s)
      Koyama S, Itatani K, Kyo S, Aoyama R, Tubokou Y, Fujimoto H, Harada K.
    • Journal Title

      Ann Thorac Cardiovasc Surg.

      Volume: in-press

    • NAID

      130002583825

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Aortic valve replacement and concomitant coronary artery bypass grafting in a patient with infective endocarditis and anomalous origin of the right coronary artery from the opposite sinus of Valsalva2012

    • Author(s)
      Koyama S, Itatani K, Kyo S, Aoyama R, Tubokou Y, Fujimoto H, Harada K
    • Journal Title

      Ann Thorac Cardiovasc Surg

    • NAID

      130002583825

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The lower limit of the pulmonary artery index for the extracardiac Fontan circulation2012

    • Author(s)
      Itatani K, Miyaji K. Reply to the editor
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: 143(4) Pages: 990-990

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 先天性大動脈疾患の血流シミュレーションにおける反射波応答を加味した境界条件の検討2012

    • Author(s)
      宮崎翔平, 板谷慶一, 劉 金龍, 銭 逸, 宮地 鑑, 横田 元, 小野 稔, 梅津光生
    • Journal Title

      日本機械学会 バイオエンジニアリング講演会

    • Related Report
      2012 Final Research Report
  • [Journal Article] Subacute presentation of right ventricular perforation after pacemaker implantation.2012

    • Author(s)
      Koyama S, Itatani K, Kyo S, Aoyama R, Ishiyama T, Harada K, Ono M.
    • Journal Title

      Ann Thorac Cardiovasc Surg.

      Volume: 19(1): Pages: 73-5

    • NAID

      10031176198

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of surgical arch reconstruction methods on single ventricle workload in the Norwood procedure.2012

    • Author(s)
      Itatani K, Miyaji K, Qian Y, Liu JL, Miyakoshi T, Murakami A, Ono M, Umezu M.
    • Journal Title

      J Thorac Cardiovasc Surg.

      Volume: 144 Pages: 130-138

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Half-turned truncal switch operation for transposition of great arteries with ventricular septal defect and pulmonary regurgitation2011

    • Author(s)
      Myaji K, Itatani K, Inoue N, Ishii M
    • Journal Title

      Interact Cardiovasc Thorac Surg

      Volume: 13(2) Pages: 217-9

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Left ventricular assist device support with a centrifugal pump for 2 months in a 5-kg child2011

    • Author(s)
      Inoue T, Nishimura T, Murakami A, Itatani K, Takaoka T, Kitahori K, Umeki A, Takezoe T, Kashiwa K, Kyo S, Ono M
    • Journal Title

      J Artif Organs

    • NAID

      10030339118

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 先天性大動脈疾患の血流シミュレーションにおける境界条件と乱流モデルの検討2011

    • Author(s)
      宮崎翔平, 板谷慶一, 劉 金龍, 銭 逸, 宮地 鑑, 横田 元, 小野 稔, 梅津光生
    • Journal Title

      日本流体力学会数値流体シンポジウム

    • Related Report
      2012 Final Research Report
  • [Journal Article] The effectiveness of high-flow regional cerebral perfusion in Norwood stage I palliation2011

    • Author(s)
      Miyaji K, Miyamoto T, Kohira S, Yoshii T, Itatani K, Inoue N
    • Journal Title

      Eur J Cardiothorac Surg

      Volume: 40(5) Pages: 1215-20

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The lower limit of the pulmonary artery index for the extracardiac Fontan circulation2011

    • Author(s)
      Itatani K, Miyaji K, Nakahata Y, Ohara K, Takamoto S, Ishii M
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: 142(1) Pages: 127-35

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of surgical arch reconstruction methods on single ventricle workload in the Norwood procedure2011

    • Author(s)
      Itatani K, ,, , Miyaji K, Qian Y, Liu JL, Miyakoshi T, Murakami A, Ono M, Umezu M
    • Journal Title

      J Thorac Cardiovasc Surg

      Volume: 144 Pages: 130-8

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure2011

    • Author(s)
      Liu JL, Qian Y, Itatani K, Murakami A, Shiurba R, Miyakoshi T, Miyaji K, Umezu M
    • Journal Title

      BMEI

      Pages: 318-23

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] An approach of computational hemodynamics for cardiovascular flow simulation2011

    • Author(s)
      Liu JL, Qian Y, Itatani K, Miyakoshi T, Murakami A, Ono M, Shiurba R, Miyaji K, Umezu M
    • Journal Title

      AJK2011-03057

      Pages: 1449-1456

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] 先天性大動脈疾患の血流シミュレーションにおける境界条件と乱流モデルの検討2011

    • Author(s)
      宮崎翔平, 板谷慶一, 劉 金龍, 銭 逸, 宮地 鑑, 横田 元, 小野 稔, 梅津光生
    • Journal Title

      日本流体力学会数値流体シンポジウムプロシーディング

      Volume: 1 Pages: 1-10

    • Related Report
      2011 Annual Research Report
  • [Journal Article] An approach of computational hemodynamics for cardiovascular flow simulation.2011

    • Author(s)
      Liu JL, Qian Y, Itatani K, Miyakoshi T, Murakami A, Ono M, Shiurba R, Miyaji K, Umezu M
    • Journal Title

      AJK2011

      Volume: 03057 Pages: 1449-1456

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure.2011

    • Author(s)
      Liu JL, Qian Y, Itatani K, Murakami A, Shiurba R, Miyakoshi T, Miyaji K, Umezu M
    • Journal Title

      BMEI

      Volume: 1 Pages: 318-23

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effectiveness of high-flow regional cerebral perfusion in Norwood stage I palliation.:2011

    • Author(s)
      Miyaji K, Miyamoto T, Kohira S, Yoshii T, Itatani KI, Inoue N.
    • Journal Title

      Eur J Cardiothorac Surg.

      Volume: 0 Pages: 1215-20

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 血流速度ベクトルを測って活かす2013

    • Author(s)
      板谷慶一
    • Organizer
      第77回日本循環器学会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-15
    • Related Report
      2012 Final Research Report
  • [Presentation] ベクトルを用いて心臓血管内の血流を"診る"VFM (Vector Flow Mapping)2013

    • Author(s)
      板谷慶一
    • Organizer
      第24回日本心エコー図学会
    • Place of Presentation
      第24回日本心
    • Related Report
      2012 Final Research Report
  • [Presentation] VFM (Vector Flow Mapping)がもたらす循環生理学と循環器診療への新たな視点2013

    • Author(s)
      板谷慶一
    • Organizer
      第24回日本心エコー図学会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Novel blood flow visualization technique with echocardiography and its application to the cardiovascular surgery2013

    • Author(s)
      Keiichi Itatan
    • Organizer
      Asian Cardiovascular and Thoracic Surgery
    • Place of Presentation
      神戸
    • Related Report
      2012 Final Research Report
  • [Presentation] A novel approach to aortic insufficiency based on quantitative cardiac workload estimation from visualized blood flow with MRI and echocardiography2013

    • Author(s)
      Keiichi Itatani
    • Organizer
      Asian Cardiovascular and Thoracic Surgery 2013
    • Place of Presentation
      神戸
    • Related Report
      2012 Final Research Report
  • [Presentation] Novel Blood Flow Visualization Technique with Echocardiography and its Applications to the Cardiovascular Surgery2013

    • Author(s)
      Keiichi Itatani
    • Organizer
      Asian Cardiovascular and Thoracic Surgery 2013
    • Place of Presentation
      神戸
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] A Novel Approach to Aortic Insufficiency Based on Quantitative Cardiac Workload Estimation from Visualized Blood Flow with MRI and Echocardiography2013

    • Author(s)
      Keiichi Itatani
    • Organizer
      Asian Cardiovascular and Thoracic Surgery 2013
    • Place of Presentation
      神戸
    • Related Report
      2012 Annual Research Report
  • [Presentation] ベクトルを用いて心臓血管内の血流を“診る” VFM (Vector Flow Mapping)2013

    • Author(s)
      板谷慶一
    • Organizer
      心エコー図学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] VFM (Vector Flow Mapping)がもたらす 循環生理学と循環器診療への新たな視点2013

    • Author(s)
      板谷慶一
    • Organizer
      心エコー図学会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 血流速度ベクトルを測って活かす2013

    • Author(s)
      板谷慶一
    • Organizer
      日本循環器学会
    • Place of Presentation
      横浜
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 渦を測ってみよう VFM2012

    • Author(s)
      板谷慶一
    • Organizer
      日本心エコー図学会秋の講習会
    • Place of Presentation
      東京
    • Year and Date
      2012-10-07
    • Related Report
      2012 Final Research Report
  • [Presentation] ベクトルを用いて心臓血管内血流を診る:超音波による新たな血流可視化ソフトウェアVFM(Vector Flow Mapping)2012

    • Author(s)
      板谷慶一
    • Organizer
      第3回 相模心臓血管外科懇話会
    • Place of Presentation
      神奈川
    • Year and Date
      2012-09-22
    • Related Report
      2012 Final Research Report
  • [Presentation] 左冠動脈多肢病変における血流動態から見た至適なバイパスグラフトデザイン2012

    • Author(s)
      小山紗千, 板谷慶一, 山本匡, 宮崎翔平, 小川大輔, 朴栄光, 小野稔, 梅津光生
    • Organizer
      第17回日本冠動脈外科学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-12
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓血管内血流をベクトルで求める方法について2012

    • Author(s)
      板谷慶一
    • Organizer
      第76回 日本循環器学会ランチョンセミナー
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Related Report
      2012 Final Research Report
  • [Presentation] Quantitative evaluation of the hemodynamics in Fontan circulation2012

    • Author(s)
      本田崇, 板谷慶一, 木村純人, 中畑弥生, 宮地鑑, 石井正浩
    • Organizer
      76回日本循環器学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2012-03-16
    • Related Report
      2012 Final Research Report
  • [Presentation] 血行動態から見た多肢病変における至適バイパスグラフトデザイン2012

    • Author(s)
      小山紗千, 板谷慶一, 山本匡, 宮崎翔平, 朴栄光, 小野稔, 梅津光生
    • Organizer
      第65回日本胸部外科学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] カラードップラで満足していますか2012

    • Author(s)
      板谷慶一
    • Organizer
      第23回 日本心エコー図学会 イブニングセミナー
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 先天性大動脈疾患の血流シミュレーションにおける反射波応答を加味した境界条件の検討2012

    • Author(s)
      宮崎翔平, 板谷慶一, 劉金龍, 銭逸, 宮地鑑, 横田元, 小野稔, 梅津光生
    • Organizer
      日本機械学会バイオエンジニアリング講演会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 心臓血管内血流をベクトルで求める方法について2012

    • Author(s)
      板谷慶一
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 血行動態から見た多枝病変における至適冠動脈バイパスグラフ トデザイン2012

    • Author(s)
      小山紗千, 板谷慶一, 山本匡, 宮崎翔平, 小川大輔, 朴栄光, 小野稔, 梅津光生.
    • Organizer
      第65回日本胸部外科学会総会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] Quantative evaluation of the hemodynamics in Fontan circulation2012

    • Author(s)
      本田 崇, 板谷慶一, 木村純人, 中畑弥生, 宮地 鑑, 石井正浩
    • Organizer
      第76回日本循環器学会学術集会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 先天性大動脈疾患の血流シミュレーションにおける反射波応答を加味した境界条件の検討2012

    • Author(s)
      宮崎翔平, 板谷慶一, 劉 金龍, 銭 逸, 宮地 鑑, 横田 元, 小野稔, 梅津光生
    • Organizer
      日本機械学会 バイオエンジニアリング講演会
    • Place of Presentation
      大阪
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 左冠動脈多枝病変における血流動態からみた至適なバイパスグラフトデザイン2012

    • Author(s)
      小山紗千, 板谷慶一, 山本匡, 宮崎翔平, 小川大輔, 朴栄光, 小野稔, 梅津光生
    • Organizer
      第17回日本冠動脈外科学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
    • Invited
  • [Presentation] 新たなVector Flow Mapping と臨床応用の可能性2011

    • Author(s)
      板谷慶一
    • Organizer
      第84回 日本超音波医学会 シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-05-27
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 磁気共鳴イメージング装置、画像処理装置、画像診断装置、画像解析装置、MRI画像作成方法およびプログラム2013

    • Inventor(s)
      板谷慶一 宮地鑑 宮崎翔平 高橋哲彦
    • Industrial Property Rights Holder
      北里大学、株式会社日立メディコ
    • Filing Date
      2013-05-08
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 血流可視化診断装置2012

    • Inventor(s)
      板谷慶一 小野稔
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2012-05-25
    • Related Report
      2012 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 流体流速検出装置及びプログラム2012

    • Inventor(s)
      板谷慶一 小野稔 岡田孝
    • Industrial Property Rights Holder
      国立大学法人東京大学、日立アロカメディカル株式会社
    • Filing Date
      2012-03-16
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 血流可視化診断装置2012

    • Inventor(s)
      板谷慶一 小野稔
    • Industrial Property Rights Holder
      板谷慶一 小野稔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-05-25
    • Related Report
      2011 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 流体流速検出装置及びプログラム2012

    • Inventor(s)
      板谷慶一 小野稔 岡田孝
    • Industrial Property Rights Holder
      板谷慶一 小野稔 岡田孝
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Patent(Industrial Property Rights)] 流体流速検出装置2012

    • Inventor(s)
      板谷慶一 小野稔 岡田孝
    • Industrial Property Rights Holder
      板谷慶一 小野稔 岡田孝
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-10-17
    • Related Report
      2011 Annual Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 血流可視化診断装置及びプログラム2011

    • Inventor(s)
      板谷慶一 小野稔
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2011-11-28
    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 血流可視化診断装置及びプログラム2011

    • Inventor(s)
      板谷慶一 小野稔
    • Industrial Property Rights Holder
      板谷慶一 小野稔
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-11-25
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2011-09-05   Modified: 2019-07-29  

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