Allergenicities of the multiple individual parvalbumins in fish

• Project/Area Number: 23K07899
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 54020:Connective tissue disease and allergy-related
• Research Institution: Fujita Health University
• Principal Investigator: J・M Dijkstra 藤田医科大学, 医科学研究センター, 講師 (10387681)
• Co-Investigator(Kenkyū-buntansha): 近藤 康人 藤田医科大学, 医学部, 教授 (30301641)
• Project Period (FY): 2023-04-01 – 2026-03-31
• Project Status: Granted (Fiscal Year 2023)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2025: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2023: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: allergy / fish / parvalbumin / molecular biology

Outline of Research at the Start

Many people are allergic against fish meat parvalbumins. We will check reactivities of patient antisera against the various, recombinantly produced, parvalbumins ofマダイ(Pagrus major), マダラ (Gadus macrocephalus), and サケ (Oncorhynchus keta). We hope that this will help to understand fish meat allergies.