Development of indicators to evaluate the international health regulation core capacity in the post-COVID-19 era

Research Project

Project/Area Number	23K09693
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Research Institution	Nagasaki University
Principal Investigator	玉記雷太長崎大学, 熱帯医学研究所, 准教授 (40507919)
Co-Investigator(Kenkyū-buntansha)	金子聰長崎大学, 熱帯医学研究所, 教授 (00342907) 井上真吾長崎大学, 熱帯医学研究所, 教授 (00346925) ンゾウサムソン長崎大学, 熱帯医学研究所, 客員准教授 (20816714) 古瀬祐気東京大学, 新世代感染症センター, 教授 (50740940)
Project Period (FY)	2023-04-01 – 2026-03-31
Project Status	Granted (Fiscal Year 2023)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2025: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2024: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2023: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	IHR / Sub-Sahara Africa / DPM / Post-CVOID-19 / 国際保健規則 / サブサハラアフリカ / 動的準備指標 / 評価指標開発
Outline of Research at the Start	COVID-19パンデミックによって、国際保健規則（International Health Regulations: IHR）のコアキャパシティ（特に感染症のアウトブレイクを検知し対応する能力）の評価と実際のキャパシティの乖離が示された。適正な感染症政策策定のために新しいIHR評価指標の開発は喫緊のグローバル課題である。本研究は、新興再興感染症発生リスクの高いサブサハラアフリカを対象に、既存のIHRコアキャパシティ評価指標をレビューし、定量・定性分析から、妥当性・適時性・持続可能性を担保したIHRコアキャパシティ指標の開発を行い、グローバルな感染症対策枠組みに資するエビデンスを示す。
Outline of Annual Research Achievements	The activities conducted in the first year of the research were as follows: Development of Indicators: Given the Post-COVID-19 context, a preparatory period was allocated for the systematic review of indicators for International Health Regulations (IHR) core capacities in regions of Africa at high risk for emerging and re-emerging infectious diseases. International Collaboration and Workshop Organization: Workshops aimed at enhancing research capacity were held in conjunction with key personnel from major infectious disease laboratories in Kenya, Ghana, the Democratic Republic of the Congo, and Zambia, under the annual meeting of the Tropical Medicine Society. These workshops evaluated the research and surveillance capabilities of the IHR core capacities in these countries. Collaboration with WHO: Meetings with representatives from the World Health Organization (WHO) were conducted to review the current WHO IHR strategies and Dynamic Preparedness Metric (DPM). These activities aimed to review the surveillance and response capabilities for infectious diseases in Africa and serve as critical background information for the research. Based on these insights, the drafting of the research paper is currently underway.
Current Status of Research Progress	Current Status of Research Progress 2: Research has progressed on the whole more than it was originally planned. Reason The first year's preparation period is progressing almost as planned. However, there is a delay in the progress of the qualitative study on surveillance sensitivity in Kenya due to the limited availability of a research collaborator in charge.
Strategy for Future Research Activity	In the second year, the following activities will be carried out to lead to results in the third year: Continue analysis and move towards publication on the existing key assessment indicators related to IHR core capacities, research capacity in Africa, and resource disparities. Consider alternatives for external hindering factors affecting the qualitative study on metadata. These alternatives may include collaboration with Kenya based Japanese researchers (additional co-researchers) and/or the use of secondary data. Collaborate with WHO resource persons and monitor the progress of the DPM group under the IHR core capacities as the study advances.