Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2025: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2024: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2023: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Outline of Research at the Start |
Deciphering how senescent cells and tissue deliver the signals and messages, are at the nexus of mechanisms involved in longevity and age-related metabolic dysfunction. Multi-tissue/organ crosstalk, defined as the mutual biological communication between distant tissue or organs mediated by signaling factors, may transmit aging signals initiated by the early-senescent cell/tissue/organs, spreading the aging signal. The present study aims to discuss how aging signals are conveyed by senescent cells and organs, to other cells and organs, as well as the underlying mechanisms.
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